NCT07106021Active, not recruitingPhase 1/2
A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease
A Phase 1b/2a Study Assessing the Safety and Efficacy of Intraputamenal Dopaminergic Stem Cell Transplants in Patients With Idiopathic Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 27 Jul 2026
Brief summary (registry, in English)
This clinical trial is designed to test the safety and tolerability of the study intervention, RNDP-001, which will be implanted into the brain of study participants during a surgical procedure.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 12 (estimated)
- First submitted
- 21 Jul 2025
- Start date
- 17 Jul 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- Kenai Therapeutics
- Diseases
- Parkinson disease
- NCT number
- NCT07106021
What you commit to
- Study type: Interventional · Phase 1/2
- Planned participants: 12
- From 17 Jul 2025 to the primary completion date, Sept 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous infusion therapy or surgery for Parkinson's disease
Other illness
- Known Parkinson's disease gene mutation or variant
- History of allergic reaction or intolerance to an immunotherapeutic agent
- Clinically significant medical conditions likely to interfere with the surgical procedure or study assessments
Other
- Contraindication to MRI
Who the study is looking for
- Diagnosis of idiopathic Parkinson's disease consistent with the Movement Disorders Society Clinical Criteria
- Age 45 to 75
- Medically stable to undergo a surgical procedure
Age in the registry: 45 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Ohio State University -Wexner Medical Center Coordinator of this site? Confirm its status | Columbus | United States | Unknown status |
| Keck Medical Center of University of Southern California Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
| University of Arizona Coordinator of this site? Confirm its status | Tucson | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.