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NCT07106294Recruiting

Hyperspectral Imaging for Prediction of Preeclampsia

Systematic Evaluation of Hyperspectral Analysis as a Predictive Marker of Preeclampsia

Source: ClinicalTrials.gov · Last updated 4 Sept 2026

Brief summary (registry, in English)

Preeclampsia is a hypertensive pregnancy disorder that can quickly lead to serious, potentially life-threatening outcomes for both the mother and the fetus. Typical features of preeclampsia are by endothelial and microvascular dysfunctionsNotably, such impairments in endothelial function may precede preeclampsia diagnosis and canpersist for years postpartum. In clinical practice, however, no predictive methods have yet been established that specifically reflect endothelial dysfunction in the context of preeclampsia. Hyperspectral imaging represents a new and non-invasive imaging modality that allows contact-free visualization of peripheral microcirculatory dynamics and tissue perfusion. Despite its growing use in other medical fields, this technology has not yet been systematically studied to determine its predictive potential in preeclampsia. The HIPPA project (Systematic Evaluation of Hyperspectral Analysis for Prediction of Preeclampsia) is a prospective observational study to evaluate the applicability of hyperspectral imaging as a new tool for prediction of preeclampsia.

Status (registry)
Recruiting
Study type
Observational
Enrollment
1430 (estimated)
First submitted
21 Jul 2025
Start date
21 Aug 2025
Primary completion date
1 Jul 2027
Lead sponsor
Heidelberg University
NCT number
NCT07106294

What you commit to

  • Study type: Observational
  • Planned participants: 1430
  • From 21 Aug 2025 to the primary completion date, 1 Jul 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • lack of consent
  • language barrier
  • severe fetal chromosomal/genetic/structural anomalies known at study enrollment
  • smoking in the last two hours before measurement
  • diagnosis of preeclampsia at study enrollment

Who the study is looking for

  • singleton pregnancies
  • age ≥ 18 years
  • patient's ability to provide consent
  • written informed consent
  • women scheduled for a routine ultrasound scan in first or second trimester

Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Heidelberg University Hospital, Department of Gynecology and Obstetrics
Coordinator of this site? Confirm its status
HeidelbergGermanyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.