NCT07106359Recruiting
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
A Randomized Controlled Pilot Trial of a Behavioral Intervention to Increase Uptake of Genetic Services Among Relatives at Risk of Lynch Syndrome
Source: ClinicalTrials.gov · Last updated 21 Jul 2026
Brief summary (registry, in English)
The purpose of the study is to see if our education materials help people at risk for Lynch syndrome decide about seeking genetic services. Untested relatives of patients with Lynch syndrome will be recruited to complete a baseline survey and will be randomized to receive either the an information letter or an information letter plus a booklet. Two follow-up surveys will be administered over the span of 6 months. Participants will also be invited to join an optional exit interview to provide feedback.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 185 (estimated)
- First submitted
- 30 Jul 2025
- Start date
- Sept 2025
- Primary completion date
- Aug 2027
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- Colorectal cancer
- NCT number
- NCT07106359
What you commit to
- Study type: Interventional
- Planned participants: 185
- From Sept 2025 to the primary completion date, Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Probands Inclusion Criteria:
- English speaking
- at least 18 years old
- have had genetic testing for Lynch syndrome (LS)
- do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening)
- Clinical Trial Participants Inclusion Criteria:
- English-speaking
- at least 18 years old
- a blood relative of a patient who was diagnosed with LS
- potentially at risk for LS
- have not scheduled or had pre-test genetic counseling or genetic testing for LS
- do not have a personal history of a cancer (excluding non-melanoma skin cancer)
- do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UAB Coordinator of this site? Confirm its status | Birmingham | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.