NCT07107568Recruiting
Assessment of Coronary Artery Disease Before Transcatheter Aortic Valve Replacement: A Randomized, Multicenter, Non-Inferiority Trial
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to determine whether a non-invasive coronary assessment strategy using photon-counting detector computed tomography (PCD-CT) is non-inferior to invasive coronary angiography (ICA) for evaluating coronary artery disease (CAD) prior to transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 700 (estimated)
- First submitted
- 28 Jul 2025
- Start date
- 14 Aug 2025
- Primary completion date
- 31 Dec 2029
- Lead sponsor
- Medical University Innsbruck
- Diseases
- Coronary artery disease
- NCT number
- NCT07107568
What you commit to
- Study type: Interventional
- Planned participants: 700
- From 14 Aug 2025 to the primary completion date, 31 Dec 2029
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe renal impairment with an estimated glomerular filtration rate of \<30 mL/min/1.73 m²
- Life expectancy \<1 year due to other severe non-cardiac disease (e.g., malignancy)
Other
- Cardiogenic shock at presentation (e.g., emergency indication for TAVR)
- Pregnancy
Who the study is looking for
- Age ≥ 18 years
- Severe aortic valve stenosis and indication for intervention according to current European Society of Cardiology (ESC) guidelines
- TAVR candidate
- Written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of Innsbruck Coordinator of this site? Confirm its status | Innsbruck | Austria | Recruiting |
| Department of Internal Medicine II, Cardiology and Intensive Care Medicine, Klinikum Wels-Grieskirchen Coordinator of this site? Confirm its status | Wels | Austria | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.