NCT07112521Recruiting
tDCS Intervention in Breast Cancer Survivors With and Without Obesity Reporting Cognitive Impairment
Evaluating the Efficacy of Home-Based tDCS for Cancer-Related Cognitive Impairment and Its Moderation by Obesity: A Double-Blind Randomized Controlled Trial.
Source: ClinicalTrials.gov · Last updated 2 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this intervention is to investigate whether transcranial Direct Current Stimulation (tDCS) can alleviate Cancer-Related Cognitive Impairment (CRCI) in breast cancer survivors, as measured by changes in brain structures and cognitive performance. To assess the efficacy of tDCS, the investigators will compare outcomes between participants receiving active stimulation and those receiving sham stimulation (a placebo condition where participants believe they are receiving stimulation, but are not). Participants will: * Undergo a baseline MRI session * Receive either active or sham tDCS for six weeks * Undergo a follow-up MRI session * Complete cognitive tests and respond to psychosocial questionnaires before, during, and after the tDCS intervention
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 2 Jul 2025
- Start date
- 1 Sept 2025
- Primary completion date
- Jan 2027
- Lead sponsor
- University of Helsinki
- Diseases
- Obesity
- NCT number
- NCT07112521
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Sept 2025 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have received primary cancer treatment (chemotherapy, radiotherapy, immunotherapy, or surgery) within the last 3 months
Other illness
- Have a history of childhood-onset cancer
- Diagnosed with dementia, Alzheimer's disease, multiple sclerosis, or - Parkinson's disease
- Have a history of stroke or transient ischemic attack
- Have any of the following medical implants or devices: cardiac implantable electronic devices, metallic intraocular foreign bodies, neurostimulation systems, cochlear/ear implants, drug infusion pumps, catheters with metal components, metallic fragments (e.g., bullets), cerebral aneurysm clips, magnetic dental implants, tissue expanders, artificial limbs, non-removable piercings, or face tattoos.
Other
- Present with acute eczema on the scalp
- Have experienced unconsciousness for more than five minutes due to a head/brain injury within the last 10 years
- Suffer from claustrophobia
- Are pregnant or breastfeeding
- Weight exceeding 250 kg (the MRI table weight limit) or they are unable to fit within the 70 cm diameter bore of the MRI machine
Who the study is looking for
- Female
- Over 18 years old
- Diagnosed with primary adult-onset breast cancer within the last 5 years
- Completed all active cancer treatments at least 3 months prior to study participation
- Capable of fulfilling study requirements, including having internet access.
- Fluent in either Finnish or English
- Have normal or corrected vision and hearing
- Right-handed (based on the Edinburgh Handedness Inventory score; Oldfield, 1971)
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Psychology, Faculty of Medicine, University of Helsinki Coordinator of this site? Confirm its status | Helsinki | Finland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.