NCT07112820Recruiting
Contribution of Myocardial Perfusion Imaging in the Initial Assessment of Acute Coronary Syndromes Without ST Elevation for the Diagnosis of Myocardial Infarction or Differential Diagnoses
Source: ClinicalTrials.gov · Last updated 8 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Patients with myocardial infarction require invasive treatment involving coronary angiography to confirm the diagnosis and, in most cases, treatment by angioplasty/stenting. Trans-thoracic ultrasound is central to the initial management of patients admitted to hospital with acute coronary syndrome without ST segment elevation. The aim of our study is therefore to compare perfusion ultrasound with coronary angiography and MRI in this population in order to determine whether the performance is satisfactory.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 1 Aug 2025
- Start date
- 24 Jun 2024
- Primary completion date
- 31 Jul 2026
- Lead sponsor
- Fondation Hôpital Saint-Joseph
- Diseases
- Coronary artery disease
- NCT number
- NCT07112820
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 24 Jun 2024 to the primary completion date, 31 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient with a known allergy to ultrasound contrast medium
- Patient with a caricatured picture of myocarditis (fever and/or significant biological inflammatory syndrome with CRP\>50mg/l)
Age
- Pregnant or breastfeeding patients (negative pregnancy test for women of childbearing age)
Other
- Haemodynamically unstable patient: HR \> 100 and/or systolic blood pressure \< 90 mmHg and/or diastolic blood pressure \< 60 mmHg and/or oxygen saturation \< 92% in AA and/or clinical signs of hypoperfusion (mottling, cyanosis)
- Rhythmically unstable patient: sustained ventricular tachycardia, sudden death recovered.
- Patient with ST segment elevation.
- Patient with a contraindication to MRI.
- Patients already included in a type 1 interventional research protocol (RIPH1)
- Patients under guardianship or curatorship
- Patients deprived of their liberty
- Patients under judicial protection
Who the study is looking for
- Patient over 18 years of age
- Hospitalised in cardiology as an emergency for acute coronary syndrome without ST segment elevation with indication for coronary angiography within 72 hours of admission
- Not yet undergone coronary angiography.
- Troponin \>99th percentile, i.e. \>27ng/l (troponin I, hypersensitive, Abbott)
- With de novo segmental kinetic disorder on TTE or ECG repolarisation disorder outside ST elevation
- Patient affiliated with a health insurance scheme
- French-speaking patient
- Patient who has given their free, informed and written consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Paris Saint-Joseph Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.