NCT07113457Active, not recruiting
Assessing Upper Extremity Function in Chronic Stroke Survivors Through Acute Intermittent Hypoxia
Assessing Upper Extremity Function in Chronic Stroke Survivors: Enhancing Neural Recovery With Acute Intermittent Hypoxia
Source: ClinicalTrials.gov · Last updated 20 Mar 2026
Brief summary (registry, in English)
Here we aim to observe effects of acute intermittent hypoxia in persons who have experienced a single stroke. We have previously shown this technique to be safe and effective at increasing strength in persons with disabilities, and here are aiming to determine the mechanism of how the breathing method modulates motor function.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 22 Jul 2025
- Start date
- 2 Jun 2025
- Primary completion date
- Aug 2026
- Lead sponsor
- Shirley Ryan AbilityLab
- Diseases
- Stroke
- NCT number
- NCT07113457
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 2 Jun 2025 to the primary completion date, Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of prior neurological disorders
Other illness
- Brain stem or cerebellar stroke; mean Fazekas score rated on initial fluid-attenuated inversion recovery MRI greater than equal to 3
- Pre-existing hypoxic pulmonary disease
- Includes positive Covid-pneumonia diagnosis within 1 year of screening visit
- Severe hypertension (\>160/100)
- Any ischemic cardiac disease
Other
- Severe Aphasisa
Who the study is looking for
- A first time, unilateral, ischemic, hemispheric stroke, confirmed by MRI
- Chedoke stage of hand assessment \>= 3
- Ability to open and close affected hand
- Able to understand and communicate in english
- Able to independently consent
- over 6 months post stroke
- Must have a hemoglobin level above 10g/dl
- Must have ability to leave research visit with a compainon/group trasportation
- WOCBP must be comfortable confirming negative pregnancy prior to hypoxia
- Must not be involved in any other research intervention study testing upper extremities
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shirley Ryan AbilityLab Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.