NCT07114770Recruiting
Explore the Impacts of One Session and Multiple Session Theta Burst Stimulation Over Cerebellum in Adults With Autism Spectrum Disorder
Source: ClinicalTrials.gov · Last updated 11 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to establish a personalized theta burst stimulation (TBS, an advanced variant of repetitive transcranial magnetic stimulation, rTMS) protocol considering autistic idiosyncrasy (interindividual variability).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 4 Aug 2025
- Start date
- 29 Jul 2025
- Primary completion date
- 30 Jun 2028
- Lead sponsor
- Chang Gung Memorial Hospital
- Diseases
- Autism
- NCT number
- NCT07114770
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 29 Jul 2025 to the primary completion date, 30 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous or current severe neurological disorders, especially epilepsy
- Previous or current severe systemic diseases such as cardiovascular disease, diabetes or hypertension
- Previous or current severe brain injury
- Implementation of metal materials such as a pacemaker or medication pump
- Previous or current severe psychiatric disorders such as schizophrenia, bipolar disorder, severe major depressive disorder or substance abuse
- Previous brain surgery or central nerve system infection
- Concurrent use of medications which increased the risk of seizure attack
- Concurrent use of antiepileptic drugs
- Start to use antiepileptic drugs during study period
Other illness
- Have experienced sleep disorders during brain stimulation
- Seizure attack during the study period
Other
- Pregnancy
- Intracranial space occupied lesions
- Participate in another clinical trial within one month
- With damaged skin at the stimulated region
- With multiple sclerosis
- With large ischemic scars
- Severe alcoholism
- Uncontrollable migraines due to increased intracranial pressure
- Unsuitable for MRI (e.g. those with claustrophobia)
- Unsuitable for EEG
- DSM-5 severity level of ASD: level 3
- Suicidal ideation within one year
- Withdrawal criteria:
- Autistic symptoms worsened obviously during the study period (change of DSM-5 severity level)
- Extreme agitation or irritability during the study period
- Participants request
- Clinical symptoms worsened obviously during study period
- Suicidal ideation or self-harm behaviors during study period
Who the study is looking for
- Autistic adults (≥18 years old), confirmed by Autism Diagnostic Observation Schedule.
- DSM-5 severity level of ASD: level 1 or level 2
- ≥18 years old without autism spectrum disorder
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chang Gung Memorial Hospital Coordinator of this site? Confirm its status | Taoyuan | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.