NCT07115563Recruiting
Daily Amino Acid Supplementation for People With Parkinson's Disease
Effects of Targeted Amino Acid Supplementation for People With Parkinson's Disease on Amino Acid Profiles and Health Related Markers
Source: ClinicalTrials.gov · Last updated 13 Aug 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if a tailored amino acid supplement works to help adults living with Parkinson's disease to improve nutrition, metabolic function, body composition, and physical and mental function. The main questions it aims to answer are: Does the tailored amino acid supplement increase essential amino acids (nutritional status)? Does the tailored amino acid supplement increase an antioxidant (complex amino acid) and decrease an amino acid associated with oxidative stress? Does the tailored amino acid supplement improve physical and mental health compared to a placebo supplement? Researchers will compare the tailored amino acid supplement to a placebo (a look-alike substance that contains no active ingredients) to see if the tailored amino acid supplements work to support health for people with Parkinson's disease. Participants will: Take the tailored amino acid supplement or a placebo every day for 6 months, visit the lab at baseline, after 3 months, and after 6 months for fasting blood draws, body composition assessment, and physical and mental health testing and keep a diary of their food intake and supplement intake.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 29 Jul 2025
- Start date
- 31 Oct 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- Cristina Colon-Semenza
- Diseases
- Parkinson disease
- NCT number
- NCT07115563
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 31 Oct 2025 to the primary completion date, Sept 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Inclusionary Criteria:
- Male and Females.
- 50-80 Years.
- Previous diagnosis of idiopathic Parkinson's Disease by patient report.
- Use of dopamine replacement medication (e.g. levodopa) for at least 2 years.
- On a stable dose of dopamine replacement medication for at least 3 months with no plans for change in the next two months.
- Exclusionary criteria
- Apparent cognitive impairment as determined by phone screening (Telephone Interview for Cognitive Status \<29).
- Diagnosis of Parkinsonism or atypical Parkinson's Disease.
- Prescription of Dopamine antagonist.
- Any unstable medical condition.
- Use of Deep Brain Stimulation.
- Gastric or Bowel resection surgery.
- Contraindications to blood draw.
Age in the registry: 50 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UConn Health Coordinator of this site? Confirm its status | Farmington | United States | Recruiting |
| University of Connecticut Coordinator of this site? Confirm its status | Storrs | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.