NCT07116083Recruiting
µQFR for Branch Stenosis After Single Stent in Bifurcation Lesions
Diagnostic Performance of µQFR for Residual Functional Stenosis in Bifurcation Lesions After Single-stenting Strategy
Source: ClinicalTrials.gov · Last updated 2 Feb 2026
Brief summary (registry, in English)
Murray-law based single-view quantitative flow ratio (µQFR) has been recommended for guiding percutaneous coronary intervention (PCI) in selective patients. However, it's reliability has not been validated in bifurcation lesions which present complex anatomy and flluid conditions before and after PCI. The goal of this study is to investigate the diagnostic performance of µQFR in side branch after single-stent treatment for bifurcation lesions in patient with obstructive coronary artery diseases.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 290 (estimated)
- First submitted
- 28 Jul 2025
- Start date
- 13 Aug 2025
- Primary completion date
- 30 Aug 2026
- Lead sponsor
- Shanghai Zhongshan Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT07116083
What you commit to
- Study type: Observational
- Planned participants: 290
- From 13 Aug 2025 to the primary completion date, 30 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute myocardial infarction.
- Cardiogenic shock or severe heart failure (Killip class IV).
- Known allergy to iodinated contrast media.
- History of coronary artery bypass graft surgery.
Lab values
- Serum creatinine \> 150 μmol/L or estimated glomerular filtration rate (eGFR) \< 45 mL/min/1.73 m² calculated using the CKD-EPI formula.
Who the study is looking for
- Age ≥ 18 years and provision of written informed consent for biospecimen donation upon hospital admission.
- Clinical suspicion or diagnosis of CAD requiring coronary angiography and physiological assessment.
- Angiographically confirmed true bifurcation lesions, including but not limited to: left main-left anterior descending-left circumflex (LM-LAD-LCx), left anterior descending-diagonal (LAD-Dg), left circumflex-obtuse marginal (LCx-OM), and right coronary artery-posterior left ventricular-posterior descending artery (RCA-PLV-PDA).
- Bifurcation lesion vessel diameter ≥ 2.5 mm with visually estimated angiographic diameter stenosis ≥ 50%.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zhongshan Hospital,Fudan University Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.