NCT07116330Recruiting
Late-Onset Seizures: Trial of Vascular Risk Investigation and Treatment
Source: ClinicalTrials.gov · Last updated 3 Mar 2026
Brief summary (registry, in English)
A growing body of evidence suggests patients with late-onset seizures are at an increased risk of stroke, but the potential for reducing cardiovascular morbidity through risk factor screening and management is unknown. The investigators aim to determine whether individuals with new-onset unprovoked seizures after middle age should undergo vascular risk assessment. In a cluster project the investigators assess the effect of vascular risk factor screening in an observational study as well as a cohort study. The project has two interlinked components: a prospective single group study, in which risk factor assessment is performed and subsequent management is followed for one year; and a register-based cohort study examining the long-term effects of the intervention on a system level.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 420 (estimated)
- First submitted
- 10 Jun 2025
- Start date
- 1 Sept 2025
- Primary completion date
- Dec 2027
- Lead sponsor
- Sahlgrenska University Hospital
- Diseases
- Epilepsy
- NCT number
- NCT07116330
What you commit to
- Study type: Observational
- Planned participants: 420
- From 1 Sept 2025 to the primary completion date, Dec 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- preexisting seizures/epilepsy, as demonstrated by a registered diagnostic code for seizures (ICD-10: R568, G40, G41) or a dispensed antiseizure medication (ATC-code: N03) more than 3 months before the initial consultation
Other illness
- Progressive brain disease (tumour or degenerative)
- Register study:
- a registered diagnostic code for stroke or TIA (ICD-10: I61, I63, I64, or G45 except G454) before the initial consultation, or
- progressive brain disease, as indicated by diagnostic codes or drug prescriptions suggestive of brain tumors (ICD-10: C71, D33, D43, C793) or
- neurocognitive disorders (ICD-10: F00-F03, F051, G30, G318, G912; ATC code: N06D).
Other
- Clinical study:
- Inability to consent.
Who the study is looking for
- Clinical study:
- \- First assessment for unprovoked seizures or epilepsy with onset after age 50 -- - vascular risk factor evaluation per the new routine at participating care givers
- Register study:
- age ≥50 with a first-ever outpatient appointment to one of the participating clinics and
- a first-listed diagnostic code for seizures or epilepsy (ICD-10: R568, G40)
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Södra Älvsborg Sjukhus Coordinator of this site? Confirm its status | Borås | Sweden | Recruiting |
| Salgrenska University hospital Coordinator of this site? Confirm its status | Gothenburg | Sweden | Recruiting |
| Skånes universitetssjukhus Coordinator of this site? Confirm its status | Malmö | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.