NCT07119827Recruiting
Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury
Neuropsychology and Personality: Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury
Source: ClinicalTrials.gov · Last updated 2 Jul 2026
Brief summary (registry, in English)
This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke. The secondary aims are to assess the effects of premorbid personality on the sort- and long-term recovery in autonomy (disability), cognitive functions, psycho-behavioral functioning, motor skills, and social participation. Evaluate the incidence of premorbid personality alterations. Investigate personality changes 12-18 months after the neurological event.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 250 (estimated)
- First submitted
- 5 Aug 2025
- Start date
- 1 May 2025
- Primary completion date
- 1 May 2028
- Lead sponsor
- Universita di Verona
- Diseases
- Stroke
- NCT number
- NCT07119827
What you commit to
- Study type: Observational
- Planned participants: 250
- From 1 May 2025 to the primary completion date, 1 May 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Pre-existing neurological pathology
- Severe aphasia or severe inattention that precludes administration of the tests required by the protocol, as identified during cognitive screening.
- Patients with a language barrier due to insufficient proficiency in Italian.
- Particularly vulnerable populations:
- The following patients will be excluded from the study: patients in emergency situations.
Who the study is looking for
- diagnosis of one of the following two conditions:
- Severe Acquired Brain Injury (sABI) of traumatic or non-traumatic etiology; the term sABI includes acute brain injuries of traumatic or non-traumatic origin (vascular, infectious, metabolic, or anoxic), in which the patient initially presents with a coma state (Glasgow Coma Scale - GCS less than 8) and simultaneously exhibits motor, sensory, cognitive, and/or behavioral impairments.
- Ischemic or hemorrhagic stroke without features of Severe Acquired Brain Injury (sABI) (Glasgow Coma Scale \[GCS\] score ≥ 8 and no alteration of consciousness).
- Time from injury between:
- 7 and 90 days for Severe Acquired Brain Injury (sABI) patients
- 3 and 30 days for stroke patients
- Level of Cognitive Functioning (LCF) score ≥ 6 for sABI patients
- Signed informed consent for study participation
- Presence of a support family member (caregiver) able to assist with completing the personality questionnaire (HEXACO Adjective Scale, HAS)
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sezione medicina fisica e riabilitativa dipartimento di neuroscienze, verona Coordinator of this site? Confirm its status | Verona | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.