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NCT07123259Completed

Ulcer Pomegranate Muffins

Anti-Ulcerative Colitis Activity of Pomegranate (Punica Granatum L.) Peel Powder Muffins in Patients With Gastric Ulcer

Source: ClinicalTrials.gov · Last updated 19 Aug 2025

Brief summary (registry, in English)

Pomegranate (Punica granatum L.) peel powder, known for its potent antioxidant, anti-inflammatory, and antimicrobial properties, has shown promise in the dietary management of gastrointestinal disorders. In recent clinical observations, incorporating pomegranate peel powder into muffins consumed by patients with gastric ulcers demonstrated potential anti-ulcerative colitis activity. The bioactive compounds in the peel, such as polyphenols (punicalagins, ellagic acid), help reduce oxidative stress and modulate inflammatory pathways in the gut. Patients consuming these enriched muffins reported improvements in gastrointestinal symptoms, reduced mucosal inflammation, and enhanced mucosal healing, suggesting a supportive role of pomegranate peel as a functional food ingredient in managing gastric and colitis-related conditions.

Status (registry)
Completed
Study type
Interventional
Enrollment
82 (actual)
First submitted
7 Aug 2025
Start date
10 Aug 2024
Primary completion date
10 Oct 2024
Lead sponsor
University of Lahore
NCT number
NCT07123259

What you commit to

  • Study type: Interventional
  • Participants enrolled: 82
  • From 10 Aug 2024 to the primary completion date, 10 Oct 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • current use of proton pump inhibitors (PPIs)

Other illness

  • history of gastric surgery

Other

  • pregnancy or lactation

Who the study is looking for

  • Both male and female patients aged 45-60 years with confirmed Helicobacter pylori
  • infection verified through a stool antigen test (pH 7.0-7.5)
  • elevated levels of pepsinogen I and II

Age in the registry: 40 years to 60 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Sana Noreen
Coordinator of this site? Confirm its status
LahorePakistanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.