NCT07125313Recruiting
Effect of Yoga Training on Cardiovascular and Mental Health Parameters in Hypertensive Patients
Effect of Yoga Training on Cardiovascular, Autonomic, Mental Health and Cognitive Parameters in Hypertensive Patients: a Randomized Controlled Clinical Trial (Hypertension and Yoga Study)
Source: ClinicalTrials.gov · Last updated 22 Jun 2026
Brief summary (registry, in English)
The objective of this study will be to analyze the effect of 16 weeks of Yoga training on cardiovascular, autonomic, mental health, and cognitive parameters in hypertensive individuals. This is a randomized, controlled clinical trial to be conducted with adults and elderly (40 years or older), of both sexes, diagnosed with High Blood Pressure (HBP), who will be randomized into two groups: Yoga Group (YG) and Control Group (CG). The YG will undergo a Yoga training program involving breathing techniques, mobility, physical postures, relaxation, and meditation for 16 weeks. In the first eight weeks (phase 1), three supervised weekly sessions will be held. In the last eight weeks of the study (phase 2), the training will consist of three supervised weekly sessions and the delivery of an asynchronous video lesson, with the weekly frequency then increasing (from three to four sessions per week). The video lesson will be available on a digital platform. Before, after eight weeks, and after 16 weeks, cardiovascular, autonomic, mental and cognitive health parameters will be assessed. Furthermore, the biomarkers Brain-Derived Neurotrophic Factor (BDNF), serotonin, and nitric oxide will be analyzed at different assessment times of the study, as well as biochemical profile tests (glucose, total cholesterol, among others), functional capacity tests, and body composition. This project is expected to contribute to the literature by better elucidating the effects of Yoga on the cardiovascular, mental, and cognitive health of hypertensive individuals. The SPSS (21.0) statistical package will be used for data analysis. After confirming the appropriate assumptions, generalized estimating equations will be used, followed by the Bonferroni post hoc test, with a significance level of 5%.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 23 Jul 2025
- Start date
- 11 Aug 2025
- Primary completion date
- 20 Dec 2026
- Lead sponsor
- Universidade Federal de Santa Catarina
- Diseases
- High blood pressure
- NCT number
- NCT07125313
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 11 Aug 2025 to the primary completion date, 20 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Change in the class and/or dose of antihypertensive medication during the study
Other illness
- Diagnosis of other diseases during the study
- Worsening of the disease (resting systolic blood pressure (BP) \> 180 mmHg).
Other
- Adherence of less than 75% of training sessions
- Adherence to another physical exercise program
Who the study is looking for
- Adults or elderly individuals
- \>= 40 years
- Both sexes
- Diagnosis of hypertension controlled by up to three medications
- Who do not present high cardiovascular risk
- Who have not engaged in a physical exercise program in the six months prior to the start of the study will participate in the study.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universidade Federal de Santa Catarina Coordinator of this site? Confirm its status | Florianópolis | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.