NCT07126132Completed
Hpx•apoB Product as a Biomarker for Coronary Artery Disease
The Hemopexin-Apolipoprotein B Product: A Novel Biomarker Integrating Oxidative Stress and Lipid Metabolism for Coronary Artery Disease Risk Stratification
Source: ClinicalTrials.gov · Last updated 17 Aug 2025
Brief summary (registry, in English)
This was a single-center, cross-sectional study designed to investigate a novel composite biomarker, the Hemopexin-Apolipoprotein B (Hpx•apoB) product, for its association with coronary artery disease (CAD). The study aimed to determine if the Hpx•apoB product could serve as an independent predictor for the presence and severity of CAD and to evaluate its incremental value in improving risk stratification when added to existing clinical risk models.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 460 (actual)
- First submitted
- 10 Aug 2025
- Start date
- 1 Jan 2019
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Shiyan City Renmin Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT07126132
What you commit to
- Study type: Observational
- Participants enrolled: 460
- From 1 Jan 2019 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute infectious or systemic inflammatory diseases.
- Malignancy.
- Autoimmune disease.
- A history of major surgery within the past three months.
Lab values
- Severe hepatic or renal dysfunction (eGFR \< 30 mL/min/1.73m²).
Who the study is looking for
- Aged ≥18 years.
- Referred for coronary angiography due to suspected or known CAD.
- Provided written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Renmin Hospital, Hubei University of Medicine Coordinator of this site? Confirm its status | Shiyan | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.