NCT07128823Completed
Effects of Accelerated Skill Acquisition Programme With Segmental Vibration on Upper Limb in Stroke.
Combined Effects of Accelerated Skill Acquisition Programme With Segmental Vibration on Extensor Muscles for Upper Limb Function in Subacute Stroke.
Source: ClinicalTrials.gov · Last updated 18 Feb 2026
Brief summary (registry, in English)
Stroke is a major health burden and the leading cause of serious long-term disability around the world. One of the most cumbersome deficits after a unilateral stroke is impairment in the contralateral upper limb. Segmental vibration is an intervention that incorporates sensory stimulation to improve motor cortical excitability. This study aims to investigate the influence of a 15-minute SMV application along with accelerated skill acquisition programme (ASAP) on spasticity, motor function, manual dexterity, and somatosensory function of the Upper Limb in Subacute stroke. This study will be a randomized clinical trial conducted in the physiotherapy department of DHQ Hospital Gujranwala, Gondal Hospital, and Dayan Physiotherapy and Rehabilitation over 10 months. Using the Online Randomizer tool, 60 stroke patients will be recruited through a non-probability convenience sampling technique and randomly divided into two equal groups, Group A and Group B. Group A will receive ASAP with high-frequency segmental vibration(100Hz) on the extensor muscles while Group B, will receive accelerated skill acquisition programme (ASAP) with only. The Assessment tools are the Fugl-Meyer Assessment Scale (for upper limb function), Wolf Motor Functional Test(for motor function), Modified Ashworth Scale(for spasticity), Maximal Hand Grip Strength(for manual dexterity), Nottingham Sensory Assessment(for somatosensory function). Outcome measures will be assessed at baseline,4th week,8th week, and 12th week. Follow-up will be performed in the 16th week. Data analysis will be done by SPSS version 28.0. Two-way Mixed ANOVA, repeated measure ANOVA, and one-way ANOVA will be used in case of normal distribution of data. The Friedman, Kruskal Wallis, and Wilcoxon sign rank tests will be used for non-normal data.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 7 Apr 2025
- Start date
- 20 Dec 2024
- Primary completion date
- 30 Jul 2025
- Lead sponsor
- Riphah International University
- Diseases
- Stroke
- NCT number
- NCT07128823
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 20 Dec 2024 to the primary completion date, 30 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with acute or chronic neurologic or orthopedic impairments and those who experienced discomfort or had undergone surgery in the upper limbs within 6 months before the study onset.
Other illness
- Individuals with unstable medical conditions that could interfere with rehabilitation progress or pose risks during therapy sessions are typically excluded
- Patients with uncontrolled psychiatric disorders that could compromise their ability to participate in or benefit from rehabilitation are typically excluded
- Metal implants e. g cardiac pacemaker
Other
- Pain (FMA-UE pain score of 1 for at least 2 joints) in the affected UE.
- All types of aphasia.
- Visual problems that could not be corrected.
Who the study is looking for
- Unilateral stroke between 3 months and 6 months post-stroke.
- Fugl-Meyer assessment upper extremity (FMA-UE) motor scores between 19 and 58.
- Participants be able to follow the researcher's instructions and study procedures.
- Spasticity of spastic agonist muscles ranging from 0-2 on the modified Ashworth scale
- Montreal Cognitive Assessment (MoCA) score of 24 or higher, indicating sufficient cognitive function to participate in stroke rehabilitation.
Age in the registry: 45 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| DHQ Hospital Gujranwala, Gondal Hospital, and Dayan Physiotherapy and Rehabilitation Coordinator of this site? Confirm its status | Chak One Hundred Seventy-five Nine Left | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.