NCT07130175Completed
Radiofrequency Ablation for Polymorphic Ventricular Tachycardia With Heart Failure (RFCA for PMVT-HF)
Efficacy of Radiofrequency Catheter Ablation on Improving Cardiac Function in Patients With Polymorphic Ventricular Tachycardia and Coexisting Heart Failure: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 19 Aug 2025
Brief summary (registry, in English)
This is a prospective, randomized, controlled trial to investigate the efficacy of radiofrequency catheter ablation (RFCA) combined with guideline-directed medical therapy (GDMT) compared to GDMT alone in patients with polymorphic ventricular tachycardia (PMVT) and coexisting heart failure (HF). The study aims to evaluate whether the addition of RFCA can lead to superior improvements in cardiac function, clinical outcomes, and serum biomarkers at a 6-month follow-up.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 118 (actual)
- First submitted
- 12 Aug 2025
- Start date
- 31 Dec 2022
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Qian Feng
- Diseases
- Heart failure
- NCT number
- NCT07130175
What you commit to
- Study type: Interventional
- Participants enrolled: 118
- From 31 Dec 2022 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior pacemaker implantation.
- Cardiac surgery within the previous 3 months.
Other illness
- Diagnosis of a malignant tumor.
- Severe psychiatric disorders.
- History of thyroid diseases or collagen diseases.
- Recent infectious diseases.
- Coexisting coagulation disorders.
- Congenital heart disease, cor pulmonale, or other primary structural heart diseases.
Other
- Severe dysfunction of the lungs, liver, or kidneys.
- Contraindications to amiodarone.
- Pregnancy or lactation.
Who the study is looking for
- Confirmed diagnosis of polymorphic ventricular tachycardia (PMVT) and coexisting heart failure (HF) via ECG and clinical evaluation.
- New York Heart Association (NYHA) functional class II-IV.
- First-time candidate for RFCA.
- Provided written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Hospital of Zhangjiakou City Coordinator of this site? Confirm its status | Zhangjiakou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.