NCT07130539Active, not recruiting
Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension
Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training to Improve Blood Pressure and Other Cardiovascular Disease Risk Factors in Adults With Hypertension and Overweight/Obesity
Source: ClinicalTrials.gov · Last updated 19 Aug 2025
Brief summary (registry, in English)
This pilot study examines whether a 4-week diet and exercise intervention can improve blood pressure, heart health, and sleep in physically inactive individuals with high blood pressure and overweight or obesity.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 10 (actual)
- First submitted
- 12 Aug 2025
- Start date
- 11 Mar 2025
- Primary completion date
- 23 Aug 2025
- Lead sponsor
- Texas Woman's University
- Diseases
- Obesity, High blood pressure
- NCT number
- NCT07130539
What you commit to
- Study type: Interventional
- Participants enrolled: 10
- From 11 Mar 2025 to the primary completion date, 23 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current use of sleep medications or sleep aids
- Current use of metformin, insulin, dietary supplements or drugs for glycemic control or weight loss
- A "yes" response to any questions on the PAR-Q (excluding Question 6 on use of BP medications)
- Prior hospitalization for COVID-19
- Any medications or supplements that may alter study outcomes as determined by study PI
Other illness
- Food allergy or lactose intolerance
- History of diagnosed cardiovascular diseases including heart attack, stroke, irregular heartbeat such as atrial fibrillation, coronary artery or peripheral artery disease, or heart failure
- History of liver, kidney, or metabolic disease (including type I or II diabetes)
- History of cancer
- Diagnosed moderate to severe obstructive sleep apnea, CPAP use, insomnia, h/o other sleep disorder
- History of gastric bypass or other weight loss surgery
Other
- Pregnant, breastfeeding, lactating
- Current smoker
- Height \> 6 foot 6 inches (78 inches)
- Blood pressure ≥ 160/100 mm Hg (Contraindication to exercise testing)
- Night shift and/or rotating shift worker (current or in the past 2 years)
- Excessive alcohol intake - ≥ 8 drinks per week in women, ≥ 15 drinks per week in men
- Weight stable for the last 2 months (\< 5 pounds body weight change)
- Currently following a special diet for weight loss (Keto, Atkins, Intermittent Fasting)
- Exercise training (≥ 2 days per week structured aerobic and resistance training at gym)
Who the study is looking for
- Age 18 to 74 years old
- BMI 25 - 39.9 kg/m2 (for measured BMI)
- Clinically diagnosed hypertension (physical medical record showing diagnosis of hypertension) with or without current medication use (SPB \< 160 mm Hg, DBP \< 100 mm Hg)
- Physically inactive \< 7,500 steps per day (measured on Fitbit over 1-week)
- No current injury, illness, or joint issue that prevents participation in exercise
- Able to read and speak English
- Willingness to participate and give informed written consent
- Willingness to share medical record indicating diagnosis of HTN and current medication use
Age in the registry: 18 years to 74 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Texas Woman's University Houston Center Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.