NCT07134296Not yet recruiting
Magnetic Resonance Imaging (MRI)-Guided Rectal Cancer Preservation Program
MRI-guided Rectal Cancer Preservation Program
Source: ClinicalTrials.gov · Last updated 21 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to learn if the use of MRI-guided irradiation increases the rates of rectal preservation
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- First submitted
- 12 Aug 2025
- Start date
- 1 Oct 2025
- Primary completion date
- 30 Jun 2030
- Lead sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
- Diseases
- Colorectal cancer
- NCT number
- NCT07134296
What you commit to
- Study type: Interventional
- Planned participants: 32
- From 1 Oct 2025 to the primary completion date, 30 Jun 2030
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patient unable to undergo an MRI examination
Who the study is looking for
- Patients aged 18 or older with primary Stage II (T3-4, N0) or Stage III (any T, N1-2) biopsy-proven rectal cancer
- No prior radiation therapy to the target areas;
- ECOG 0-2 with medical status not contraindicating treatment with radical intent including TNT and TME (if required) and with basal laboratory values as follows:
- Absolute neutrophil count (ANC) ≥ 1,000 cells/mm3
- Platelets ≥ 50,000 cells/mm3.
- Hemoglobin ≥ 8.0 g/dl.
- Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \< 4 x upper limit of normal.
- Total bilirubin \< 2 x upper normal mg/dL.
- Alkaline phosphatase \< 4 x upper limit of normal.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.