NCT07134621Enrolling by invitation
Target Organ Damage in Patients With Repaired Coarctation of Aorta and Exercise Induced Hypertension
Source: ClinicalTrials.gov · Last updated 30 Apr 2026
Brief summary (registry, in English)
The goal of this observational study is to obtain data on the effect of exercise induced hypertension on target organs in adult patients with repaired coarctation of the aorta. The main questions it aims to answer are: * patients with exercise induced hypertension have signs of hypertensive heart disease? * patients with exercise induced hypertension have increased arterial stiffness? * patients with exercise induced hypertension have signs of hypertensive renal damage? Participants will be invited for an outpatient appointment during which medical history and physical investigation will be performed. They will undergo cardiopulmonary exercise testing during which blood pressure will be measured regularly. Transthoracic echocardiography will also be performed as well as assessment of arterial stiffness by measuring pulse wave velocity. Renal function will be assessed by blood and urine analysis.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 14 Aug 2025
- Start date
- 16 Jul 2025
- Primary completion date
- Jun 2026
- Lead sponsor
- University Medical Centre Ljubljana
- Diseases
- High blood pressure
- NCT number
- NCT07134621
What you commit to
- Study type: Observational
- Planned participants: 50
- From 16 Jul 2025 to the primary completion date, Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- antihypertensive therapy
Other illness
- arterial hypertension at rest
- associated haemodynamically significant valvular heart disease
- associated complex congenital heart disease
- advanced heart failure
- symptomatic arrhythmias
Other
- haemodynamically significant recoarctation
- cognitive or physical limitations to perform exercise stress testing
Who the study is looking for
- adult patients aged 18 years and older
- history of coarctation of aorta repair
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UMC Ljubljana Coordinator of this site? Confirm its status | Ljubljana | Slovenia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.