NCT07135869Completed
Muscle Fatigue in People With Cystic Fibrosis: Insight From a Mobile App
Reliability and Discriminant Validity of a Mobile App for Detecting Muscle Fatigue in People With Cystic Fibrosis
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
Muscle fitness is an important component of health. For instance, the ability to resist to muscle fatigue development is important for daily functioning. Previous studies have suggested altered muscle function in people with cystic fibrosis. However, it is unclear whether such findings still apply in the modern era of CF. Several studies suggested that recent improvements in therapeutics, including CFTR modulators, may have positive effects on the skeletal muscles, potentially normalizing the ability to resist to muscle fatigue. However, no studies to date compared muscle fatigue between people with cystic fibrosis and healthy controls in a large sample of patients. One difficulty is that muscle fatigue assessment requires high-cost dynamometric instruments, which also leads to a gap between research and clinical practice. Our research group has created a mobile application based on video analysis of the chair rising test that reports values of time, velocity and power as reliable as devices found in a laboratory environment. The application has been shown to be valid and reproducible for measuring muscle fatigue in healthy people. However, a validation is necessary before recommending its use in people with cystic fibrosis.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 100 (actual)
- First submitted
- 14 May 2025
- Start date
- 1 Sept 2025
- Primary completion date
- 12 May 2026
- Lead sponsor
- Universidad Católica San Antonio de Murcia
- Diseases
- Cystic fibrosis
- NCT number
- NCT07135869
What you commit to
- Study type: Observational
- Participants enrolled: 100
- From 1 Sept 2025 to the primary completion date, 12 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any musculoskeletal conditions that could limit or influence test performance.
Who the study is looking for
- Clinically stable.
- No changes in medication or pulmonary exacerbations within the two weeks prior to inclusion.
- Not requiring oxygen therapy during the test.
- No history of lung or liver transplants.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Asociación Murciana de Fibrosis Quistica Coordinator of this site? Confirm its status | Murcia | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.