NCT07140107Enrolling by invitation
Effectiveness of Original vs. AI-Generated Plain Language Summaries of Systematic Reviews
Patients' Perceptions and Comprehension of Original Versus AI-Generated Plain Language Summaries of Cochrane Oncology Systematic Reviews
Source: ClinicalTrials.gov · Last updated 24 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The study explores how patients with non-metastatic breast cancer perceive and comprehend original Plain Language Summary and AI-generated Plain Language Summary (PLS) of two systematic reviews from the Cochrane Library. The systematic reviews address exercise during adjuvant therapy and psychological interventions for non-metastatic breast cancer. The study, which is randomized and double-blind, aims to assess whether AI-generated PLS and original PLS differ in their influence on patients' intention to undertake and apply the recommendation presented in the summary, as well as their overall understanding of the study results.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 130 (estimated)
- First submitted
- 18 Aug 2025
- Start date
- 14 Aug 2025
- Primary completion date
- 1 Feb 2026
- Lead sponsor
- University of Split, School of Medicine
- Diseases
- Metastatic breast cancer
- NCT number
- NCT07140107
What you commit to
- Study type: Interventional
- Planned participants: 130
- From 14 Aug 2025 to the primary completion date, 1 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- female patients receiving only hormonal treatment.
Other illness
- female patients with metastatic breast cancer.
Who the study is looking for
- female patients with histologically confirmed non-metastatic breast cancer currently undergoing chemotherapy or radiotherapy:
- neoadjuvant chemotherapy (with or without immunotherapy or antiHER2 therapy),
- adjuvant chemotherapy (with or without immunotherapy or antiHER2 therapy),
- adjuvant radiotherapy (including local and locoregional radiation treatment with possible radiotherapy boost where indicated).
- patients need to be able to read and understand Croatian.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Oncology and Radiotherapy, University Hospital Split Coordinator of this site? Confirm its status | Split | Croatia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.