NCT07140588Not yet recruiting
Pilot Study of a New Nerve Grafting Method During Bladder Cancer Surgery to Help Preserve Erections.
Pilot Study of Intraoperative Somatic-Autonomic Nerve Grafting Technique to Preserve Erectile Function in Patients With Bladder Cancer Undergoing Radical Cystectomy
Source: ClinicalTrials.gov · Last updated 24 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This pilot study will evaluate the safety and 1-year erectile function recovery in 10 patients undergoing a novel Nerve Restoring Radical Cystectomy (NR-RC), which includes a genitofemoral nerve graft. Erectile function will be assessed using IIEF-5, SF-MPQ, and CEEF questionnaires at baseline and at multiple post-operative intervals (4 weeks, 3, 6, 12, and 18 months). Safety will be monitored through peri- and post-operative complications, and additional demographic and clinical data will be collected for analysis.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 25 Jul 2025
- Start date
- Sept 2025
- Primary completion date
- Sept 2028
- Lead sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
- Diseases
- Bladder cancer
- NCT number
- NCT07140588
What you commit to
- Study type: Interventional
- Planned participants: 10
- From Sept 2025 to the primary completion date, Sept 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with previous pelvic surgery
- Patients with previous pelvic radiotherapy
- Patients undergoing a concomitant cancer surgery
Other illness
- Patients with pre-existing neurologic disease
Age
- Patients aged \< 18 years at diagnosis
Other
- Legally incapable patients
- Patients who are unable to complete questionnaires and have no companion to help complete them
Who the study is looking for
- Patients undergoing standard of care radical cystectomy for bladder cancer
- Patients must have preoperative erectile function with a baseline IIEF score of ≥17
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.