NCT07142772Not yet recruiting
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk
EMeRiT: Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk
Source: ClinicalTrials.gov · Last updated 27 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study will show the value of early genetic diagnosis in the case of MEG in a child and may lead to recommendations aimed at preventing tumor risk based on a simple and easily accessible clinical criterion (the measurement of head circumference). Ultimately, this study may improve cancer prognosis in the population of children with MEG.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 23 Apr 2025
- Start date
- Sept 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Childhood cancers
- NCT number
- NCT07142772
What you commit to
- Study type: Observational
- Planned participants: 200
- From Sept 2025 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have previously undergone genetic testing as part of their MEG, with or without a diagnosis
- Patients who have not received the standard-of-care genetic analysis, specifically whole genome sequencing
Other
- Patients with an etiological diagnosis of its MEG
Who the study is looking for
- Patients with macrocephaly ≥ +3 DS due to brain MRI-confirmed MEG with or without NDD
- Patient with a proposal to investigate a genetic etiology by genome sequencing
- No objection by the patient's parents or guardians
- Patients affiliated to a social security scheme
Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| service Génétique clinique Pitié-Salpêtrière / Trousseau Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.