NCT07143656Active, not recruiting
Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational Registry
Natural History and Biomarker Correlation Study in Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational Registry
Source: ClinicalTrials.gov · Last updated 28 Aug 2025
Brief summary (registry, in English)
This retrospective observational study will analyze de-identified clinical data from patients with amyotrophic lateral sclerosis (ALS) collected at multiple centers over 7 years. The primary objective is to describe disease progression using the ALS Functional Rating Scale-Revised (ALSFRS-R). Secondary objectives include evaluating survival, ventilatory decline, and correlations between available biomarkers (e.g., neurofilament light chain, cytokines) and disease trajectory. No new interventions or patient contact will occur.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 36 (actual)
- First submitted
- 20 Aug 2025
- Start date
- 13 May 2021
- Primary completion date
- 13 Aug 2028
- Lead sponsor
- Biocells Medical
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT07143656
What you commit to
- Study type: Observational
- Participants enrolled: 36
- From 13 May 2021 to the primary completion date, 13 Aug 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients with alternative diagnoses that mimic ALS (e.g., multifocal motor neuropathy, cervical myelopathy, myasthenia gravis).
- Absence of medical records
Who the study is looking for
- Diagnosis of amyotrophic lateral sclerosis (ALS) or motor neuron disease confirmed.
- Age ≥18 years.
- Availability of at least one ALS Functional Rating Scale-Revised (ALSFRS-R) score.
- Availability of longitudinal follow-up data.
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Biocells Medical Coordinator of this site? Confirm its status | Warsaw | Poland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.