NCT07144475CompletedPhase 4
Comparison of Probiotic Effects on the Outcomes of Patients After Colorectal Cancer Surgery
Comparison of Probiotic Effects of Lactobacillus Casei Shirota With Lactobacillus Acidophilus on the Outcomes of Patients After Colorectal Cancer Surgery: A Study of Gastrointestinal Function, Sepsis Incidence, C-Reactive Protein, Interleukin 6 and Length of Stay
Source: ClinicalTrials.gov · Last updated 27 Aug 2025
Brief summary (registry, in English)
This clinical trial aims to compare the effects of administering Lactobacillus casei Shirota probiotics with Lactobacillus acidophilus on the outcomes of patients after colorectal cancer surgery. Researchers will compare probiotic to see if Lactobacillus casei Shirota improves gastrointestinal function, sepsis incidence, C-reactive protein (CRP), interleukin 6 (IL-6), and length of stay better than Lactobacillus acidophilus. Participants will take probiotics three times daily for three days before surgery.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 90 (actual)
- First submitted
- 18 Aug 2025
- Start date
- 1 Jan 2024
- Primary completion date
- 30 Nov 2024
- Lead sponsor
- Dharmais National Cancer Center Hospital
- Diseases
- Colorectal cancer
- NCT number
- NCT07144475
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 90
- From 1 Jan 2024 to the primary completion date, 30 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with chronic diseases such as HIV, uncontrolled diabetes mellitus (, uncontrolled cardiovascular disease and kidney failure
- Patients with a history of regular probiotics, or steroids, or antibiotics consumption
- Patients with anatomical disorders of the gastrointestinal system
- Patients with immunocompromised conditions.
Other
- The patient or patient's family refused to be included in the study
Who the study is looking for
- 1\. Patients who were diagnosed with colorectal cancer and would undergo resection surgery at Dharmais Cancer Hospital
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Medicine, University of Indonesia Coordinator of this site? Confirm its status | Jakarta | Indonesia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.