NCT07147010Completed
Evaluation of Correlations Between Volatile Organic Compounds and Venous Blood Glucose in Subjects With Type 2 Diabetes
Evaluation of Correlations Between Volatile Organic Compounds (VOCs) Spectra Measured With GC-IMS and MOx-sensors and Venous Blood Glucose in Subjects With Type 2 Diabetes
Source: ClinicalTrials.gov · Last updated 9 Dec 2025
Brief summary (registry, in English)
The goal of this study is to evaluate correlations between VOCs in the breath and venous blood glucose values in various glycaemic states in people living with Type 2 Diabetes. VOCs are measured with a gold-standard GC-IMS device and a prototype of a novel breath analyzer. Participants will be exposed to different blood glucose levels at different rates of change by administering glucose solution and insulin and by a meal challenge.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 21 Aug 2025
- Start date
- 1 Oct 2024
- Primary completion date
- 30 Mar 2025
- Lead sponsor
- DCB Research AG
- Diseases
- Type 2 diabetes
- NCT number
- NCT07147010
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 1 Oct 2024 to the primary completion date, 30 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently on chronic or occasional treatment with pulmonary drugs
- Participation in another investigation with an investigational drug within the 30 days preceding and during the present investigation
Other illness
- History of, or manifested, cardiovascular diseases
- Medical history of epilepsy or other neurological disease associated with seizure events
Age
- LDL not in the individual target range of an earlier cholesterol goal according ESC guideline 2021 (LDL based on last measurement by treating physician but not older than 30 days)
Other
- Pregnancy and/or lactation period
- Insulin dependency
- Smoking (last cigarette within the last six months)
- BMI above 30 kg/m²
- Lp(a) above 125 nmol/l
- Irregular 12-lead ECG or increased carotid plaque burden based on a three-point sonography. Both examinations are performed and evaluated according to the investigator's judgment.
- Known sensitivity to medical grade adhesives
- Comorbidities that are suspected to alter the VOC spectra
- Not able to understand, write or read German
Who the study is looking for
- Signed written informed consent
- T2D treated with one or more oral anti-diabetic drugs (incl GLP-1 and/or GIP)
- \< 10 years since T2D diagnosis
- HbA1c ≤8% (HbA1c based on last measurement by treating physician but not older than 120 days)
- Willingness to undergo study procedures
- Age 45 -70 years (inclusive)
Age in the registry: 45 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Inselspital Bern Coordinator of this site? Confirm its status | Bern | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.