NCT07147595Completed
Chronic Effect of Isometric Exercise on Blood Pressure in Patients With Hypertension
Chronic Effect of Isometric Exercise on Blood Pressure in Patients With Controlled Hypertension: a Randomized Clinical Trail
Source: ClinicalTrials.gov · Last updated 29 Aug 2025
Brief summary (registry, in English)
International recommendations support dynamic or isometric strength training as an adjunct to aerobic exercise. Given the lack of consensus, this study aims to evaluate the chronic effects of isometric exercise, performed through handgrip or isometric knee extension, as a hypotensive strategy in adults with hypertension.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 66 (actual)
- First submitted
- 14 Aug 2025
- Start date
- 31 Aug 2023
- Primary completion date
- 1 Sept 2023
- Lead sponsor
- Instituto de Cardiologia do Rio Grande do Sul
- Diseases
- High blood pressure
- NCT number
- NCT07147595
What you commit to
- Study type: Interventional
- Participants enrolled: 66
- From 31 Aug 2023 to the primary completion date, 1 Sept 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Pregnant women. Unstable angina. Heart failure classified as NYHA class II, III, or IV. Recent cardiovascular event within the last 3 months. Chronic renal insufficiency. Diabetes mellitus. History of malignant disease with a life expectancy of less than 2 years. Orthopedic, physical, or mental limitations that prevent the performance of physical exercise.
Who the study is looking for
- Patients with controlled hypertension under medication. Sedentary or physically inactive individuals.
Age in the registry: 40 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Instituto de Cardiologia do Rio Grande do Sul Coordinator of this site? Confirm its status | Porto Alegre | Brazil | Unknown status |
Related publications
- Four weeks of isometric handgrip training results in lower awake ambulatory blood pressure compared with control: a randomized clinical trial.Clin Physiol Funct Imaging · 2026 · PMID 42928564
This page is information, not medical advice. Discuss any trial with your doctor.