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NCT07147972Not yet recruitingPhase 3

Comparative Study of Nutraceuticals vs. Conventional Prophylactic Therapy in the Management of Migraine

Source: ClinicalTrials.gov · Last updated 29 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Migraine is a common disabling neurological condition that significantly affects quality of life. While traditional prophylactic treatments (e.g., beta-blockers, antiepileptics) are effective, they may be associated with side effects leading to poor adherence. Recent evidence suggests that nutraceuticals like magnesium, riboflavin, and coenzyme Q10 may provide a safer alternative. This study aims to compare the efficacy and tolerability of these two approaches.

Status (registry)
Not yet recruiting
Phase (registry)
Phase 3
Study type
Interventional
Enrollment
100 (estimated)
First submitted
16 Aug 2025
Start date
20 Aug 2025
Primary completion date
1 Feb 2026
Lead sponsor
Fayoum University
Diseases
Migraine
NCT number
NCT07147972

What you commit to

  • Study type: Interventional · Phase 3
  • Planned participants: 100
  • From 20 Aug 2025 to the primary completion date, 1 Feb 2026
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • • - Chronic migraine (\>15 headache days/month)
    • \- Use of other prophylactic treatments in past month
    • \- History of secondary headaches
    • \- Pregnancy or breastfeeding
    • \- Significant renal, hepatic, or cardiac disease

Who the study is looking for

  • Adults aged 18-60 years
    • \- Diagnosed with episodic migraine (ICHD-3 criteria)
    • \- ≥4 migraine attacks/month for the past 3 months
    • \- Willing to provide informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.