NCT07148297Recruiting
Colorectal Analysis for Signature Cancer Assessment Using Delta-HLD
Proof-of-concept Case-control Study for Colorectal Cancer Assessment Using Delta-HLD Technology (CASCADE)
Source: ClinicalTrials.gov · Last updated 29 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
CASCADE (Colorectal Analysis for Signature Cancer Assessment Using delta-HLD Technology) is a proof-of-concept case-control study designed to evaluate the performance of delta-HLD, Epiliquid's proprietary liquid biopsy technology, for the detection of colorectal cancer. Epiliquid also integrates a proprietary bioinformatic system capable of identifying, ranking, and selecting tumor-specific methylation biomarkers for different cancer types. In this study, colorectal cancer-specific biomarkers will be evaluated in blood and tissue samples using delta-HLD technology, which enables sensitive and multiplexed detection through PCR. Study results will support the validation of Epiliquid's integrated platform as a minimally invasive and accessible diagnostic solution for colorectal cancer.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 22 Aug 2025
- Start date
- 30 Jun 2021
- Primary completion date
- Aug 2025
- Lead sponsor
- Epiliquid Holding, Inc
- Diseases
- Colorectal cancer
- NCT number
- NCT07148297
What you commit to
- Study type: Observational
- Planned participants: 600
- From 30 Jun 2021 to the primary completion date, Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history of colorectal cancer
- Recent chemotherapy or immunosuppressive treatment
Other illness
- Inflammatory bowel disease
- Known hereditary cancer syndromes (e.g., Lynch, FAP)
- Other active malignancies
Who the study is looking for
- Candidate for colonoscopy or colorectal surgery
- Willing and able to provide informed consent
- Able to provide blood and/or tissue sample before treatment or resection
Age in the registry: 45 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Epiliquid Coordinator of this site? Confirm its status | Mendoza | Argentina | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.