NCT07149207RecruitingPhase 2
Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors
Source: ClinicalTrials.gov · Last updated 7 Jul 2026
Brief summary (registry, in English)
This study is for adult patients with head and neck cancer who are at risk of recurrence. The purpose of this study is to evaluate whether the use of Indocyanine Green (ICG) dye allows for better identification of tumor tissue during surgical procedures. Participation will include standard of care visits along with administration of ICG dye and imaging during surgery. Participation in this study will last approximately 6 weeks.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 31 Jul 2025
- Start date
- 4 May 2026
- Primary completion date
- 7 Apr 2028
- Lead sponsor
- Medical University of South Carolina
- Diseases
- Head and neck cancer
- NCT number
- NCT07149207
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 30
- From 4 May 2026 to the primary completion date, 7 Apr 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known allergy to iodides or shellfish.
Lab values
- A WOCBP who has had a positive urine or serum pregnancy test at the time of screening unless:
- they are menopausal defined by not having a menstrual cycle within the last 12 consecutive months or
- they have had a hysterectomy.
- Inadequate organ function at time of screening as defined below:
- Hepatic
- Total bilirubin \>2 x Institutional Upper Limit of Normal (IULN). Participants with a history of Gilbert's disease must have total bilirubin \<3mg/dL.
- AST (SGOT) and ALT (SPGT) \>3 x IULN.
Other
- Pregnant or breastfeeding, or expecting to conceive within the projected duration of the study.
- Currently incarcerated individuals
Who the study is looking for
- Adult subjects at least 18 years of age.
- Subjects presenting with squamous cell carcinoma of mucosal origin and are at risk for recurrence.
- Good operative candidate as determined by the treating physician and/or multidisciplinary team.
- Subject capable of giving informed consent and participating in the process of consent.
- A WOCBP must be willing and able to use highly effective contraception from the time of informed consent throughout the study period. Acceptable forms of birth control include hormonal contraceptives (such as birth control pills, skin patch, vaginal ring, injection, and/or implant), intrauterine devices (IUDs), and barrier devices (such as condoms, diaphragm, cervical cap, and sponge).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina - Hollings Cancer Center Coordinator of this site? Confirm its status | Charleston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.