NCT07149740Recruiting
Data Gathering for A10900
Source: ClinicalTrials.gov · Last updated 13 Feb 2026
Brief summary (registry, in English)
The objective of this study is to gather Optical Coherence Tomography (OCT) data on normal and diseased eyes
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 180 (estimated)
- First submitted
- 11 Jul 2025
- Start date
- 26 Jun 2025
- Primary completion date
- 1 May 2026
- Lead sponsor
- Optos, PLC
- Diseases
- Glaucoma
- NCT number
- NCT07149740
What you commit to
- Study type: Observational
- Planned participants: 180
- From 26 Jun 2025 to the primary completion date, 1 May 2026
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- No reliable visual field test result within the previous year from the study visit, defined as fixation losses \> 33% or false positives \> 33%, or false negatives \> 33% in the study eye
Other illness
- Participant has a condition or is in a situation which the investigator feels may put the participant at significant risk, may confound the study results, or may interfere significantly with the participant's participation in the study
- Participant has a condition or is in a situation which the investigator feels may put the participant at significant risk, may confound the study results, or may interfere significantly with the participant's participation in the study
- Participant has a condition or is in a situation which the investigator feels may put the participant at significant risk, may confound the study results, or may interfere significantly with the participant's participation in the study
- Participant has a condition or is in a situation which the investigator feels may put the participant at significant risk, may confound the study results, or may interfere significantly with the participant's participation in the study
- History of leukemia, dementia or multiple sclerosis
Age
- Presence of any ocular pathology except glaucoma in the study eye Inclusion Criteria for Corneal Group
- 1\. Participants 22 years of age or older on the date of informed consent 2. Participants able to understand the written informed consent and willing to participate as evidenced by signing the informed consent 3. Participants presenting at the site with corneal disease, for example but not limited to, corneal disorders due to contact lens wear, post-refractive surgery, dry eye, keratoconus 4. Participant is able to comply with the study procedures.
Other
- Participants unable to tolerate ophthalmic imaging
- Participants not able to obtain acceptable OCT images due to ocular media opacity or other reasons
- Presence of glaucoma or any ocular pathology other than a retinal pathology in the study eye as determined by self-report and/or investigator assessment at the study visit;
- Participants unable to tolerate ophthalmic imaging
- Participants not able to obtain acceptable OCT images due to ocular media opacity or other reasons
- Participants unable to tolerate ophthalmic imaging
- Participant with ocular media not sufficiently clear to obtain acceptable OCT images.
- Participants unable to tolerate ophthalmic imaging
- Participant with ocular media not sufficiently clear to obtain acceptable OCT images
Who the study is looking for
- Participants 22 years of age or older on the date of informed consent
- Participants able to understand the written informed consent and willing to participate as evidenced by signing the informed consent
- BCVA 20/40 or better in the study eye
- History of Visual field defects within the previous year from the study visit or measured the day of the study visit consistent with glaucomatous optic nerve damage with at least one of the following two findings:
- On pattern deviation (PD), there exists a cluster of 3 or more points in an expected location of the visual field depressed below the 5% level, at least 1 of which is depressed below the 1% level;
- Glaucoma hemi-field test "outside normal limits."
- Glaucomatous optic nerve damage as evidenced by any of the following optic disc or retinal nerve fiber layer structural abnormalities:
- Diffuse thinning, focal narrowing, or notching of the neuroretinal rim, especially at the inferior or superior poles with or without disc hemorrhage;
- Optic disc neural rim asymmetry of the two eyes consistent with loss of neural tissue
- Participants 22 years of age or older on the date of informed consent
- Participants able to understand the written informed consent and willing to participate as evidenced by signing the informed consent
- Participants presenting at the site with normal eyes (Cataracts, LASIK, PRK, and peripheral pathology that does not affect the posterior pole region, for example lattice and peripheral drusen, are allowed).
- BCVA 20/40 or better (each eye)
- Participant is able to comply with the study procedures
Criteria the registry did not label
- Inclusion/Exclusion Criteria Inclusion Criteria for Retinal Disease Group
- Participants 22 years of age or older on the date of informed consent
- Participants able to understand the written informed consent and willing to participate as evidenced by signing the informed consent
- BCVA 20/400 or better in the study eye
- Participants presenting at the site with retinal disease
- Diagnosis of some type of retinal pathology by investigator, may include, but not limited to: Macular Degeneration (including participants with drusen and geographic atrophy and choroidal neovascularization), Diabetic Macular Edema, Diabetic Retinopathy, Macular Hole, Epiretinal Membrane, Central Serous Retinopathy and others
Age in the registry: 22 years to - · Sex: All · Accepts healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ketchum Health Coordinator of this site? Confirm its status | Anaheim | United States | Recruiting |
| Charles Retina Institute Coordinator of this site? Confirm its status | Germantown | United States | Recruiting |
| Eye Care and Laser Surgery of Newton Wellselley Coordinator of this site? Confirm its status | Wellesley Hills | United States | Completed |
| Eye Disease Consultants, LLC Coordinator of this site? Confirm its status | West Hartford | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.