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NCT07150754Completed

Cardiological Drug Classes And Falls in Older Adults

Heart Failure Pharmacological Treatments and Falls in Older Adults: A Disproportionality Analysis of the WHO Pharmacovigilance Database

Source: ClinicalTrials.gov · Last updated 2 Sept 2025

Brief summary (registry, in English)

Heat failure is a fast gowing health issue with a rising incidence in older adults. Recommendations have recently been published to treat heart failure, but most clinical trials leading to these recommendations tended to exclude older adults. Older adults are at higher risk of falls and severe consequences of falls. All heart failure treatments are at risk of causing a fall through different mechanisms. Based on the World Health Organization global database, the main objective of this study is to investigate the association between heart failure pharmacological treatments and the report of a fall in the database. A disproportionality analysis will be performed. It will aim to assess whether some classes of heart failure drugs, and within these classes some individual drugs, are associated with a report of a fall. A sensibilty analysis will also be performed. It will aim to examine the association between takien a heart failure pharmacological treatment, with a heat failure indication and/or a loop diuretic, and the report of a fall.

Status (registry)
Completed
Study type
Observational
Enrollment
100000 (actual)
First submitted
25 Aug 2025
Start date
2 Nov 2024
Primary completion date
1 Apr 2025
Lead sponsor
University Hospital, Caen
NCT number
NCT07150754

What you commit to

  • Study type: Observational
  • Participants enrolled: 100000
  • From 2 Nov 2024 to the primary completion date, 1 Apr 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • \-

Who the study is looking for

  • Age 65 years of older

Age in the registry: 65 years to - · Sex: All

Full criteria on ClinicalTrials.gov

Sites (1)

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SiteCityCountrySite status
Caen University Hospital, Department of Pharmacology
Coordinator of this site? Confirm its status
CaenFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.