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NCT07151469Completed

Kaltenborn Versus Active Release on Temporomandibular Joint Dysfunction

Kaltenborn Mobilization Versus Active Release Technique on Temporomandibular Joint Dysfunction for Radiation - Induced Trismus in Patients With Head and Neck Cancer

Source: ClinicalTrials.gov · Last updated 12 Feb 2026

Brief summary (registry, in English)

Temporomandibular disorder (TMD) is a term describing musculoskeletal conditions of the face, jaw and temporal regions. TMD is frequently associated with pain and/or dysfunction such as impaired jaw function, pain in the temporomandibular joint (TMJ), muscles and/or related structures, and associated headaches. The etiology of TMD is multifactorial and complex. It is known that one cause of TMD symptom development is treatment for head and neck cancer (HNC). The main treatment modalities for HNC include radiotherapy (RT) with or without chemotherapy and surgical intervention, as either a single therapy or a combination therapy. In the head and neck region, the anatomical structures are necessary for essential functions such as speech, swallowing, breathing, smell, and taste. The treatment of head and neck tumors may frequently impair some of these functions, which may result in pain, oral dysfunction, and impaired health-related quality of life.

Status (registry)
Completed
Study type
Interventional
Enrollment
115 (actual)
First submitted
25 Aug 2025
Start date
1 Oct 2025
Primary completion date
1 Feb 2026
Lead sponsor
MTI University
NCT number
NCT07151469

What you commit to

  • Study type: Interventional
  • Participants enrolled: 115
  • From 1 Oct 2025 to the primary completion date, 1 Feb 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients with implants.
  • Continuing radiotherapy.
  • Subjects who received analgesics or antidepressants.

Other

  • Current metastasis.
  • Pregnant females.
  • Sensitivity to phototherapy.
  • Bell's palsy.
  • Subjects with disk displacement, arthralgia or osteoarthritis at TMJ.

Who the study is looking for

  • An experienced oral and maxillofacial surgeon will diagnose patients with temporomandibular joint disorders (myofascial pain, trismus and limitation of ROM) after head and neck cancer, patients.
  • Patients with 20 to 60 years old.
  • 6 months after ending radiotherapy.

Age in the registry: 20 years to 60 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
faculty of physical therapy, Cairo university
Coordinator of this site? Confirm its status
CairoEgyptUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.