NCT07151729Recruiting
Use of Anodal tDCS to Enhance Upper Limb Recovery in Stroke
Use of Anodal Transcranial Direct Current Stimulation to Enhance Upper Limb Recovery in Stroke
Source: ClinicalTrials.gov · Last updated 3 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This will be a randomized, blinded, sham-controlled trial. The medical device used, Soterix Medical 1x1 tDCS stimulator, is capable of delivering either real or sham tDCS and has been used in many randomised controlled trials in stroke patients. 50 patients with subacute stroke and severe upper limb weakness within 8 weeks of stroke on transfer to TTSH stroke rehab wards will be recruited over a period of 10 months. Recruited patients will be randomized into the intervention and control arms in a 1:1 ratio.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 8 Aug 2025
- Start date
- 1 Sept 2025
- Primary completion date
- 15 Sept 2026
- Lead sponsor
- Tan Tock Seng Hospital
- Diseases
- Stroke
- NCT number
- NCT07151729
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 1 Sept 2025 to the primary completion date, 15 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of brain implants, and previous insertion of external ventricular drains.
Other illness
- Metallic implants at the level of the neck, mouth cavity and below are permitted (e.g. Cardiac stents, dental implants, pacemakers and other metallic objects)
- A history of spontaneous seizures, epilepsy, brain tumour, and cranial surgery
- Severe cognitive impairment (MOCA Score \<10) that would hinder sufficient understanding of the instructions
Other
- Bilateral hemispheric or cerebellar strokes
- Pre-existing arm pathology (e.g. contracture, severe pain, etc.) on the affected side
- Pregnancy
Who the study is looking for
- First ever unilateral ischaemic or haemorrhagic stroke, as documented by CT or MRI scans
- Age 21-80 years, both males and females
- Within 8 weeks of stroke onset
- Severe weakness of one upper limb, defined by a Shoulder Abduction and Finger Extension (SAFE) score \< 5 (Medical Research Council grading)
- Provision of informed consent by patient or a legal guardian in accordance with the local ethics committee guidelines and the Declaration of Helsinki
Age in the registry: 21 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tan Tock Seng Hospital - Integrated Care Hub Coordinator of this site? Confirm its status | Singapore | Singapore | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.