NCT07153692Recruiting
Clinical Efficacy and Mechanism of tDCS for Dysphagia in PD
Clinical Efficacy and Mechanism of tDCS for Dysphagia in Patients With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 4 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to verify transcranial direct current stimulation(tDCS) efficacy for Parkinson's disease (PD)-related dysphagia and its mechanism. Subjects are randomly split into two groups: control (sham tDCS + conventional dysphagia treatment) and experimental (real tDCS + conventional treatment). Assessments will be conducted at baseline, after the completion of intervention, and at the 3-month follow-up. Swallowing function will be evaluated via gold-standard videofluoroscopic swallowing study (VFSS) and scales. Resting-state functional magnetic resonance imaging (rs-fMRI) or functional near-infrared spectroscopy (fNIRS) will be measures for tracking changes in abnormal brain regions/networks. Correlations between swallowing recovery and brain function changes, plus group imaging differences, will reveal tDCS's neurophysiological mechanism.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 58 (estimated)
- First submitted
- 5 Aug 2025
- Start date
- 17 Jul 2025
- Primary completion date
- 31 Dec 2029
- Lead sponsor
- Wang Ping
- Diseases
- Parkinson disease
- NCT number
- NCT07153692
What you commit to
- Study type: Interventional
- Planned participants: 58
- From 17 Jul 2025 to the primary completion date, 31 Dec 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having metal implants in the body
Other illness
- Comorbid with other diseases that cause dysphagia;
- Comorbid with pneumonia, or severe cardiac/renal insufficiency;
- With cognitive impairment or inability to cooperate.
Who the study is looking for
- Meet the Chinese Diagnostic Criteria for Parkinson's Disease (2016) or MDS Diagnostic Criteria for Multiple System Atrophy or Progressive Supranuclear Palsy;
- VFSS examination indicates dysphagia;
- Mini-Mental State Examination (MMSE) score \>23;
- Willing to cooperate with the study and sign the informed consent form;
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Second Affiliated Hospital of Zhejiang University School of Medicine Coordinator of this site? Confirm its status | Hangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.