NCT07155564Recruiting
Validation of Energy Expenditure Measures Study
Energy Balance Within a Whole-Room Indirect Calorimeter and Its Relevance for Energy Expenditure Measures
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
The energy that the human body burns and the amount of food consumed determine a person's body weight. If food intake covers the amount of energy burned, body weight remains constant - a state known as energy balance. Achieving an energy balance is not easy in everyday life. This is reflected in the increasing number of people suffering from morbid obesity. To counteract this development, it is important to have a better understanding of how much food a person should eat. In this study, the investigators will investigate the amount of food needed to meet a person's energy needs and bring them into energy balance. Primary aims of the study are i) to technically and biologically validate two whole-room indirect calorimeters (WRICs) and ii) by using whole-room indirect calorimetry, to achieve a more accurate estimate of a person's emergy balance compared to common approximation formulas. Secondary study aims: 1. To investigate whether the transfer of a person into energy balance using WRIC has an influence on energy expenditure measures compared to the transfer into energy balance using the usual approximation formula. 2. To investigate whether the transfer of a person into energy balance using WRIC has an influence on activity-dependent energy expenditure measures compared to the transfer into energy balance using the usual approximation formula. 3. To investigate whether differences in energy expenditure during energy balance during moderate and strenuous physical activity influence food intake. 4. To investigate whether energy intake in relation to energy expenditure during energy balance is related to weight development
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 49 (estimated)
- First submitted
- 20 Jan 2025
- Start date
- 26 Aug 2025
- Primary completion date
- 31 Jan 2029
- Lead sponsor
- University of Leipzig
- Diseases
- Obesity
- NCT number
- NCT07155564
What you commit to
- Study type: Observational
- Planned participants: 49
- From 26 Aug 2025 to the primary completion date, 31 Jan 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Nicotine abuse, Alcohol/drug abuse
Other illness
- Chronic diseases with an impact on energy expenditure
- Food allergy/intolerance, vegan diet
- Circumstances that speak against the application of wearable accelerometers (e.g. silicone contact allergy)
Lab values
- Impaired fasting glucose, diabetes mellitus and prediabetes
Other
- Weight change \> 5 kg or 5% of body weight in the last 3 months
- Strenuous physical activity in everyday life \> 1 h per day
- Body mass index \< 18.5 kg/m² or ≥ 40 kg/m²
- Pregnancy/breastfeeding
- Claustrophobia
- Refusal to communicate incidental findings
Who the study is looking for
- Abilty to provide informed consent
- Written declaration of consent
- Healthy study participants
- Able to perform moderate physical exercise using a bike ergometer
- Women: continuous contraception/fullicular phase of menstrual cycle
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Internal Medicine, Clinic for Endocrinology, Nephrology and Rheumatology, University of Leipzig Coordinator of this site? Confirm its status | Leipzig | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.