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NCT07157371Active, not recruiting

Effects of Aerobic Exercise Training Program in Females With Insulin Resistant Polycystic Ovarian Syndrome

Effects of Supervised Structured Aerobic Exercise Training Program on Serum BDNF, Androgens Level, Menstrual Irregularity and Quality of Life in Females With Insulin Resistant Polycystic Ovarian Syndrome

Source: ClinicalTrials.gov · Last updated 5 Sept 2025

Brief summary (registry, in English)

Design: RCT Randomized Clinical Trial Non Probability Convenient Sampling Technique Duration of treatment: 25 weeks 2 groups; (group A=30) SSAET +Normal routine medication+ Normal Dietary Plan , Other group (Group B=30) with normal routine medication + Normal Dietary Plan. Patients will be enrolled in experimental group according to speeds test. HYPOTHESIS: Alternate hypothesis: There is difference on the effects of Supervised Structured Aerobic Exercise Training Program on serum BDNF, androgens level, menstrual irregularity and quality of life in females with insulin resistant polycystic ovarian syndrome. Null Hypothesis: There is no difference on the effects of Supervised Structured Aerobic Exercise Training Program on serum BDNF, androgens level, menstrual irregularity and quality of life in females with insulin resistant polycystic ovarian syndrome. OBJECTIVES: To determine the effects of Supervised Structured Aerobic Exercise Training Program on quality of life in women with PCOS. 2\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on BDNF levels in women with PCOS. 3\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on mental health (stress, depression, anxiety) in women with PCOS. 4\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on BMI in women with PCOS. 5\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on menstrual irregularity in women with PCOS. 6\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on Aerobic fitness in women with PCOS. 7\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on androgens level in PCOS. 8\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on Lipid accumulation product in PCOS. 9\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on Glycemic control in PCOS.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
60 (actual)
First submitted
3 Aug 2025
Start date
1 Apr 2025
Primary completion date
30 Sept 2025
Lead sponsor
Riphah International University
NCT number
NCT07157371

What you commit to

  • Study type: Interventional
  • Participants enrolled: 60
  • From 1 Apr 2025 to the primary completion date, 30 Sept 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Any surgery in past 6 months.

Other illness

  • Any psychological disease or disorder
  • Any systemic disease other than PCOS (cushing syndrome, thyroid dysfunction, etc)
  • Orthopedic conditions (including fracture, dislocation, etc)

Other

  • Post pill PCOS, Inflammatory PCOS \& Adrenal PCOS
  • Involved in any other exercise regimen at the same time.
  • Having any specialized diet plan.

Who the study is looking for

  • Age 18 To 35 years Females.
  • Insulin resistant PCOS type.
  • Already Diagnosed patients form gynecological department according to the Rotterdam criteria.
  • Both Married and unmarried females.
  • Nulliparous females.

Age in the registry: 18 years to 35 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Sculpture Gym
Coordinator of this site? Confirm its status
LahorePakistanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.