NCT07159711Recruiting
Evaluation of Seismocardiography(SCG) for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer Surgery
Evaluation of Seismocardiography (SCG) as a Tool for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer Surgery
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
Oesophageal cancer is a common cause of cancer death worldwide. Curative treatment involves chemotherapy and surgery but has significant risks. Therefore, patient selection and improving physical fitness to withstand such major treatment is important to reduce the risk of complications. Physical fitness is traditionally measured by a specialised exercise test called Cardiopulmonary exercise testing (CPET), which can take up to one hour and requires specialised staff and expensive equipment such as a graded exercise bike or treadmill. Seismofit is a small device (smaller than a smartphone) used to estimate fitness in patients in under three minutes while lying down at rest. It measures the vibrations generated by the heart and, together with patient height, weight, age, and gender, accurately estimates fitness using an algorithm developed in healthy patients. The device has never been tested in a large group of oesophageal cancer patients to see if it can be used to predict complications in patients undergoing cancer treatment. In this study, patients undergoing Oesophageal cancer treatment with chemotherapy or chemoradiotherapy and surgery will have Seismofit measurements at various points during their treatment to see if we can predict complications and hospital stay. Secondly, this study will also evaluate the accuracy of Seismofit compared to the gold standard CPET results in cancer patients.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 164 (estimated)
- First submitted
- 17 Jul 2025
- Start date
- 1 Oct 2025
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- Guy's and St Thomas' NHS Foundation Trust
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT07159711
What you commit to
- Study type: Observational
- Planned participants: 164
- From 1 Oct 2025 to the primary completion date, 1 Jun 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients undergoing primary Oesophagectomy +/- Oesophago-Gastrectomy with no neoadjuvant therapy.
- Patient's being treated with curative intent for Oesophageal Squamous cell carcinoma
Other illness
- Patients that are deemed not fit or suitable for Oesophagogastric cancer resection as part of a Multi-Disciplinary Team meeting decision.
Age
- Patients under the age of 18.
Other
- Pregnant patients.
- Patients undergoing Neoadjuvant chemoradiotherapy.
- Patients with implanted devices such as pacemakers or cardioverter-defibrillators.
Who the study is looking for
- Age \>=18
- Diagnosis of Oesophageal cancer (T0-4 N0-3 M0, Oesophageal / Gastro-Oesophageal Junction (GOJ) type 1-2 adenocarcinoma
- Patients being considered for curative treatment (i.e. due to undergo NAC and Oesophagectomy / Oesophago-Gastrectomy \[open / MIO / hybrid / robotic\])
- Patients able to give informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal Surrey NHS Foundation Trust Coordinator of this site? Confirm its status | Guildford | United Kingdom | Active, not recruiting |
| Royal Marsden NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Guy's and St Thomas' Hospital NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| University Hospital Southampton Coordinator of this site? Confirm its status | Southampton | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.