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NCT07159711Recruiting

Evaluation of Seismocardiography(SCG) for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer Surgery

Evaluation of Seismocardiography (SCG) as a Tool for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer Surgery

Source: ClinicalTrials.gov · Last updated 14 Sept 2026

Brief summary (registry, in English)

Oesophageal cancer is a common cause of cancer death worldwide. Curative treatment involves chemotherapy and surgery but has significant risks. Therefore, patient selection and improving physical fitness to withstand such major treatment is important to reduce the risk of complications. Physical fitness is traditionally measured by a specialised exercise test called Cardiopulmonary exercise testing (CPET), which can take up to one hour and requires specialised staff and expensive equipment such as a graded exercise bike or treadmill. Seismofit is a small device (smaller than a smartphone) used to estimate fitness in patients in under three minutes while lying down at rest. It measures the vibrations generated by the heart and, together with patient height, weight, age, and gender, accurately estimates fitness using an algorithm developed in healthy patients. The device has never been tested in a large group of oesophageal cancer patients to see if it can be used to predict complications in patients undergoing cancer treatment. In this study, patients undergoing Oesophageal cancer treatment with chemotherapy or chemoradiotherapy and surgery will have Seismofit measurements at various points during their treatment to see if we can predict complications and hospital stay. Secondly, this study will also evaluate the accuracy of Seismofit compared to the gold standard CPET results in cancer patients.

Status (registry)
Recruiting
Study type
Observational
Enrollment
164 (estimated)
First submitted
17 Jul 2025
Start date
1 Oct 2025
Primary completion date
1 Jun 2027
Lead sponsor
Guy's and St Thomas' NHS Foundation Trust
NCT number
NCT07159711

What you commit to

  • Study type: Observational
  • Planned participants: 164
  • From 1 Oct 2025 to the primary completion date, 1 Jun 2027
  • 4 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients undergoing primary Oesophagectomy +/- Oesophago-Gastrectomy with no neoadjuvant therapy.
  • Patient's being treated with curative intent for Oesophageal Squamous cell carcinoma

Other illness

  • Patients that are deemed not fit or suitable for Oesophagogastric cancer resection as part of a Multi-Disciplinary Team meeting decision.

Age

  • Patients under the age of 18.

Other

  • Pregnant patients.
  • Patients undergoing Neoadjuvant chemoradiotherapy.
  • Patients with implanted devices such as pacemakers or cardioverter-defibrillators.

Who the study is looking for

  • Age \>=18
  • Diagnosis of Oesophageal cancer (T0-4 N0-3 M0, Oesophageal / Gastro-Oesophageal Junction (GOJ) type 1-2 adenocarcinoma
  • Patients being considered for curative treatment (i.e. due to undergo NAC and Oesophagectomy / Oesophago-Gastrectomy \[open / MIO / hybrid / robotic\])
  • Patients able to give informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (4)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Royal Surrey NHS Foundation Trust
Coordinator of this site? Confirm its status
GuildfordUnited KingdomActive, not recruiting
Royal Marsden NHS Foundation Trust
Coordinator of this site? Confirm its status
LondonUnited KingdomRecruiting
Guy's and St Thomas' Hospital NHS Foundation Trust
Coordinator of this site? Confirm its status
LondonUnited KingdomRecruiting
University Hospital Southampton
Coordinator of this site? Confirm its status
SouthamptonUnited KingdomRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.