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NCT07160959Not yet recruiting

Physical Exercise to Prevent Mild-cognitive Impairment in Patients With Kidney Disfunctions

Physical Exercise to Prevent Mild-cognitive Impairment Progression in Advanced Chronic Kidney Disease (CKD) and Dialysis Patients

Source: ClinicalTrials.gov · Last updated 8 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

This research project focuses on improving memory and thinking (cognitive function) in people with advanced chronic kidney disease (CKD), a condition that affects about 10% of adults and is often linked to cognitive problems. The study includes a clinical trial where patients will either receive standard care or follow a home-based exercise program involving walking and strength training, to see if regular physical activity can improve brain function. It also includes a large-scale analysis of data from the UK Biobank to explore blood and genetic markers, brain imaging, and lifestyle factors linked to cognitive health. The ultimate aim is to find effective, easy-to-implement strategies and early warning signs that could lead to better treatment and quality of life for people living with CKD.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
124 (estimated)
First submitted
16 Aug 2025
Start date
1 Jan 2026
Primary completion date
30 Apr 2028
Lead sponsor
Biogem s.c.ar.l.
NCT number
NCT07160959

What you commit to

  • Study type: Interventional
  • Planned participants: 124
  • From 1 Jan 2026 to the primary completion date, 30 Apr 2028
  • 6 sites in 6 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Absolute contraindication to exercise training (e.g. unstable angina, major amputation, severe heart failure, etc.)

Lab values

  • Uncorrected anemia (Hb \<9 g/dl)

Other

  • Known life expectancy \< 6-month
  • Non-provision of informed consent

Who the study is looking for

  • CKD at KDOQI stage 4-5
  • concomitant MCI (MOCA - MMSE (17 \< MoCA \< 26) or (16 \< MMSE \< 24)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (6)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Zurich
Coordinator of this site? Confirm its status
ZurichSwitzerlandUnknown status
Assistance Publique - Hôpitaux de Paris (AP-HP), Division of Geriatry
Coordinator of this site? Confirm its status
ParisFranceUnknown status
Biogem
Coordinator of this site? Confirm its status
Ariano IrpinoItalyUnknown status
Lithuanian University of Health Sciences
Coordinator of this site? Confirm its status
KaunasLithuaniaUnknown status
University Medical Center Groningen, Department of Nephrology
Coordinator of this site? Confirm its status
GroningenNetherlandsUnknown status
Medical University of Warsaw, Department of Nephrology, Dialysis and Internal Medicine
Coordinator of this site? Confirm its status
WarsawPolandUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.