NCT07163858Recruiting
Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery
Comparison of Hemodynamic Management by Postural Mobilization Versus Chemical Vasoconstriction Using Noradrenaline Exclusively in Off-pump Coronary Artery Bypass Graft Surgery: A Prospective, Randomized, Comparative, Single-center Study.
Source: ClinicalTrials.gov · Last updated 4 Nov 2026
Brief summary (registry, in English)
This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 1 Sept 2025
- Start date
- 6 Oct 2025
- Primary completion date
- Jul 2027
- Lead sponsor
- Infirmerie Protestante de Lyon
- Diseases
- Coronary artery disease
- NCT number
- NCT07163858
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 6 Oct 2025 to the primary completion date, Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of cardiac surgery
Lab values
- Renal failure (GFR \< 40 ml/min/1.73 m²)
Other
- Contraindication to an inotropic substance (only NA will be used)
- Contraindication to passive leg raising
- Patient in a life-threatening emergency
- Bilateral iliac or common femoral artery occlusion
- EF \< 30%
- Pregnancy and breastfeeding
- Patient with bilateral thigh amputation
- Class III obesity BMI \> 40 kg/m²
Who the study is looking for
- Adult patient
- patient requiring isolated coronary bypass surgery
- Elective procedure or medical emergency
- First cardiac surgery
- Patient with an EF ≥30%
- Mandatory affiliation to a social security system
- Signed informed consent form
- Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Infirmerie Protestante de Lyon Coordinator of this site? Confirm its status | Caluire-et-Cuire | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.