NCT07164196Completed
Endometriosis-Angiopoietin-like Protein-4
Evaluation of Angiopoietin-like Protein 4 Levels in Patients With Endometriosis
Source: ClinicalTrials.gov · Last updated 10 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Endometriosis is a chronic inflammatory disease associated with pelvic pain, dyspareunia, and impaired ovarian reserve. Cancer antigen-125 (CA-125) is widely studied but limited by low specificity, while angiopoietin-like protein-4 (ANGPTL4) has emerged as a potential biomarker due to its role in angiogenesis and inflammation. In the current study it was aimed to investigate serum and peritoneal fluid ANGPTL4 levels in women with endometriosis compared to healthy controls, and to evaluate their associations with clinical symptoms, serum CA-125, and anti-Müllerian hormone levels.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 80 (actual)
- First submitted
- 2 Sept 2025
- Start date
- 5 Jun 2025
- Primary completion date
- 21 Aug 2025
- Lead sponsor
- Ankara City Hospital Bilkent
- Diseases
- Endometriosis
- NCT number
- NCT07164196
What you commit to
- Study type: Observational
- Participants enrolled: 80
- From 5 Jun 2025 to the primary completion date, 21 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cardiovascular diseases including hypertension
- Type 1 or type 2 diabetes mellitus
- Primary adrenal insufficiency
- Thyroid dysfunctions including Hashimoto thyroiditis and Grave's disease
- Renal insufficiency
- Genetic disorders in chromosome constitution or karyotype analysis including monosomy X, trisomy X and gene mutations as BMP15, FMR I, POFIB, and GDF9
- Neurologic diseases
- Psychiatric disorders
- Autoimmune diseases or syndromes including Addison's disease, autoimmune syndromes, scleroderma, Sjogren's syndrome, myasthenia gravis, inflammatory bowel diseases, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and familial Mediterranean fever
- History of any malignancy
- History of exposure to chemotherapeutic agents or radiotherapy
Other
- Morbid obesity
- Uterine fibroids
- Hepatic dysfunctions
Who the study is looking for
- Diagnosis of endometriosis for study group who underwent laparoscopic endometriosis surgery
- Healthy women for control group
Age in the registry: 18 years to 44 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ankara Bilkent City Hospital Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.