NCT07165171Not yet recruiting
Periodontal Follow-up and Glycemy in Patients With Type 2 Diabetes
Glycemy After Periodontal Treatment in Patients With Type 2 Diabetes: a Randomized Controlled Trial Comparing Innovative Versus Standard Periodontal Follow-up
Source: ClinicalTrials.gov · Last updated 10 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Diabetes is a disease in which the majority of these patients have type 2 diabetes, linked to poor use of insulin by the body. Periodontitis is a chronic disease characterized by an immuno-inflammatory reaction with local production of inflammatory mediators (IL6, TNF-alpha, etc.) and contributes to the increase in the systemic inflammatory load with increased levels of C-reactive protein. Periodontitis is frequently found in diabetic patients; it is considered a complication of diabetes. Poor glycemic control in diabetes is associated with poor periodontal health, while periodontal infection is associated with dysglycemia and increased insulin resistance. Periodontal treatment has been shown to reduce HbA1C levels and thus the risk of complications in diabetic patients. The main objective is to evaluate the impact of innovative periodontal monitoring (with reminder systems and reinforcement of advice by SMS) versus standard periodontal monitoring on the glycemic control of diabetic patients treated for periodontitis, 2 years after the start of periodontal monitoring.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 516 (estimated)
- First submitted
- 13 Aug 2025
- Start date
- 1 Oct 2025
- Primary completion date
- 1 Oct 2029
- Lead sponsor
- Hospices Civils de Lyon
- Diseases
- Type 2 diabetes
- NCT number
- NCT07165171
What you commit to
- Study type: Interventional
- Planned participants: 516
- From 1 Oct 2025 to the primary completion date, 1 Oct 2029
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient presenting uncontrolled systemic diseases and diagnosed for less than 6 months or presenting a major aggravation of a systemic pathology according to the judgment of the investigator.
Other
- Pregnant or breastfeeding women;
- Persons deprived of liberty by a judicial or administrative decision;
- Adults subject to a legal protection measure (guardianship, curatorship).
Who the study is looking for
- \-- Adult aged 18 years or older;
- Presenting with type 2 diabetes (under ALD), balanced or not, for 6 months or more;
- Having been treated in the previous 6 months for periodontitis (stages 1 to 4 according to the new classification of periodontal and peri-implant diseases EFP-AAP 2018) in one of the participating centers and presenting a clinical situation allowing the transition to the periodontal follow-up phase (; (absence or limited number of sites presenting clinical signs of persistent periodontal inflammation)
- Presenting more than 6 teeth;
- Possessing a smartphone or tablet with internet access;
- Affiliated to social security;
- Patient able to read, write and understand French
- Having signed a consent to participate in the study.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôpital Charles Foix Coordinator of this site? Confirm its status | Ivry-sur-Seine | France | Unknown status |
| Centre Hospitalo-Universitaire de Lille Coordinator of this site? Confirm its status | Lille | France | Unknown status |
| Hospices Civils de Lyon, Centre de Soins Dentaires. Coordinator of this site? Confirm its status | Lyon | France | Unknown status |
| Centre Hospitalo-Universitaire de Nantes Coordinator of this site? Confirm its status | Nantes | France | Unknown status |
| Centre Hospitalo-Universitaire de Rennes Coordinator of this site? Confirm its status | Rennes | France | Unknown status |
| Cabinet libéral Coordinator of this site? Confirm its status | Saint-Victor-de-Cessieu | France | Unknown status |
| Hopitaux Universitaires de Strasbourg Coordinator of this site? Confirm its status | Strasbourg | France | Unknown status |
| Centre Hospitalo-Universitaire de Toulouse Coordinator of this site? Confirm its status | Toulouse | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.