NCT07165262Active, not recruitingPhase 3
Effect of Different Anesthetic Drugs on Electrocorticography (ECOG).
Effect of Different Anesthetic Drugs on Electrocorticography (ECOG), Randomized Controlled Double-blinded Study
Source: ClinicalTrials.gov · Last updated 10 Sept 2025
Brief summary (registry, in English)
Prospective, double-blind, randomized-controlled study for pediatric cases scheduled for brain tumor excision with the aid of electrocorticography (ECOG). Intraoperative ECOG has been used in an effort to localize the site of epileptogenicity through the demonstration of Interictal Epileptiform Discharges (IED) persistence, frequency, and distribution. During ECOG, pharmaco-activation may be required in order to activate Interictal Epileptiform Abnormalities (IEAs). Frequency of IEAs will be measured for each drug. The effects of anesthetic agents on intraoperative ECOG, as we assume that fentanyl will be superior to ketamine.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 88 (actual)
- First submitted
- 24 Aug 2025
- Start date
- 18 Aug 2025
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Children's Cancer Hospital Egypt 57357
- Diseases
- Epilepsy, Childhood cancers
- NCT number
- NCT07165262
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 88
- From 18 Aug 2025 to the primary completion date, 31 Mar 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with hypertension, ischemic heart disease, arrhythmia, or respiratory or renal dysfunction.
Other
- guardian refusal.
Who the study is looking for
- Age (2-18) Years scheduled for brain tumor excision with aid of ECOG
- ASA physical status (II-III).
- Patient undergoing brain surgery with epileptic focus.
Age in the registry: 2 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Cancer Hospital Egypt 57357 Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
| Children Cancer Hospital 57357 Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.