NCT07166809Completed
The Effect of DNS-Based Training Combined With PFMT on LUTS and Pelvic Floor Functions in Women With MS
Dynamic Neuromuscular Stabilization Combined With Pelvic Floor Muscle Training Improves Urinary and Pelvic Floor Outcomes in Women With Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
The goal of this randomized controlled trial is to investigate whether adding Dynamic Neuromuscular Stabilization (DNS)-based training to Pelvic Floor Muscle Training (PFMT) can improve lower urinary tract symptoms (LUTS) and pelvic floor functions in women with multiple sclerosis (MS), aged 28-54 years. The main questions it aims to answer are: Does DNS combined with PFMT improve lower urinary tract symptoms more effectively than PFMT alone? Does DNS combined with PFMT enhance pelvic floor muscle function more effectively than PFMT alone? Researchers will compare PFMT alone versus PFMT combined with DNS-based stabilization exercises to see if DNS provides additional benefits. Participants will: Perform an 8-week remotely monitored Pelvic Floor Muscle Training program. In the DNS+PFMT group, complete supervised Dynamic Neuromuscular Stabilization exercises three times a week. Undergo assessments including: Urinary Symptom Profile questionnaire, International Consultation on Incontinence Questionnaire-Short Form, Overactive Bladder Questionnaire (8-item version), Vaginal palpation using the PERFECT (Power, Endurance, Repetitions, Fast contractions, Every Contraction Timed) scheme, Electromyography (muscle electrical activity measurement) for pelvic floor muscles evaluation.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 24 (actual)
- First submitted
- 27 Aug 2025
- Start date
- 1 Sept 2023
- Primary completion date
- 27 Sept 2024
- Lead sponsor
- Ondokuz Mayıs University
- Diseases
- Multiple sclerosis
- NCT number
- NCT07166809
What you commit to
- Study type: Interventional
- Participants enrolled: 24
- From 1 Sept 2023 to the primary completion date, 27 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diagnosis of urinary tract infection
- Any medical condition that could interfere with participation
Other
- Multiple sclerosis relapse within the past month
- Pregnant or within six months postpartum
Who the study is looking for
- Aged 18-65 years
- Diagnosis of multiple sclerosis with an Expanded Disability Status Scale (EDSS) score below 6
- Pelvic floor muscle strength greater than grade 1 according to the Modified Oxford Scale (MOS)
- No pelvic floor muscle training received in the previous six months
Age in the registry: 18 years to 65 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ondokuz Mayis Üniversitesi Coordinator of this site? Confirm its status | Samsun | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.