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NCT07167810Completed

Innovative Approaches to Chest Wall Reconstruction: A Comparative Study of Rigid and Flexible Techniques

Source: ClinicalTrials.gov · Last updated 15 Sept 2025

Brief summary (registry, in English)

Chest wall resections, often performed for tumors, infections, or trauma, result in significant defects that require reconstruction to restore structural integrity and functionality. The chest wall, a complex dynamic structure composed of both rigid and soft tissues, plays a vital role in protecting thoracic organs and maintaining the mechanics of respiration. Reconstruction following chest wall resection is critical not only to achieve defect closure but also to preserve respiratory mechanics and minimize postoperative complications. The primary goals include providing structural support, ensuring stability, and achieving soft tissue coverage while maintaining chest wall flexibility and minimizing pain. the main objectives of this study is to compare the postoperative pain control and recovery outcomes between chest wall reconstruction using PMMA bone cement and twisted stainless steel wires in patients undergoing chest wall reconstruction and to evaluate the impact of chest wall reconstruction with steel wires versus PMMA on chest wall recoil.

Status (registry)
Completed
Study type
Interventional
Enrollment
76 (actual)
First submitted
3 Sept 2025
Start date
1 Jan 2021
Primary completion date
30 Jun 2025
Lead sponsor
University of Health Sciences Lahore
NCT number
NCT07167810

What you commit to

  • Study type: Interventional
  • Participants enrolled: 76
  • From 1 Jan 2021 to the primary completion date, 30 Jun 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients with contraindications to surgery.

Other illness

  • Patients with pre-existing chest wall deformities or severe chronic respiratory diseases.

Other

  • Patients who undergo reoperation or develop intraoperative complications affecting the chest wall reconstruction.

Who the study is looking for

  • Patients undergoing chest wall resection due to tumors, infections, or trauma.
  • Adults aged more than 12 years.
  • Patients who provide written informed consent.

Age in the registry: 12 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Services Institute of Medical Sciences (SIMS), Services Hospital Lahore
Coordinator of this site? Confirm its status
LahorePakistanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.