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NCT07168551Not yet recruiting

Is There a Relationship Between Uric Acid Level and Liver Fibrosis in Obese Patients

Association of Hyperuricemia and Non Alcoholic Fatty Liver Disease and Liver Fibrosis Risk in Adult Obese Patients

Source: ClinicalTrials.gov · Last updated 15 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

1. Identifying the association between hyperuricemia and NAFLD can lead to early detection and prevention of liver fibrosis in adult obese patients. 2. Understanding the relationship between hyperuricemia and NAFLD can inform targeted therapy, such as urate-lowering treatment, to potentially slow disease progression. 3 - To examine the relationship between serum uric acid levels and liver fibrosis severity\*: Assessing the correlation between serum uric acid levels and the severity of liver fibrosis in adult obese patients with NAFLD. 4- To identify potential mechanisms underlying the association\*: Exploring the potential mechanisms by which hyperuricemia may contribute to the development and progression of NAFLD and liver fibrosis in adult obese patients.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
111 (estimated)
First submitted
27 Aug 2025
Start date
1 Oct 2025
Primary completion date
1 Oct 2026
Lead sponsor
Assiut University
NCT number
NCT07168551

What you commit to

  • Study type: Observational
  • Planned participants: 111
  • From 1 Oct 2025 to the primary completion date, 1 Oct 2026
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • excessive alcohol consumption ( \> 20 gm /day in men and 10 in g /day in women )
    • 2- use of steatogenic within the past 6 months
    • 3- positive test for hepatitis B surface antigen and hepatitis B core antibody
    • 4- Drug induced liver injury and autoimmune hepatitis
    • 5 - cirrhosis and other causes of liver disease

Who the study is looking for

  • Age: Adults (typically 18-65 years old)
    • 2 - Body Mass Index (BMI): Obese patients with a BMI ≥ 30 kg/m²
    • 3- Hyperuricemia : Elevated serum uric acid levels (typically \> 7 mg/dL for men and \> 6 mg/dL for women)

Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.