NCT07169292Not yet recruiting
Effects of Wet-Cupping on Polycystic Ovary Syndrome Patients
Effects of Wet-Cupping on Polycystic Ovary Syndrome Patients: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 11 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate whether wet cupping therapy (Hijama) can improve reproductive and metabolic outcomes in women diagnosed with Polycystic Ovary Syndrome (PCOS). This study will be conducted among female participants aged 20-40 years who have been diagnosed with PCOS according to the Rotterdam criteria. The main questions it aims to answer are: Can wet cupping therapy regulate menstrual cycles in women with PCOS? Can it increase the pregnancy rate in married participants with PCOS-related infertility? Researchers will compare outcomes between a wet cupping group and a control group to determine whether Hijama has significant effects on reproductive, hormonal, and metabolic markers. Participants will: Undergo screening and eligibility evaluation using a checklist Be randomized into either the wet cupping (intervention) or control group Receive lifestyle counseling (diet and physical activity) For the intervention group: Receive one Hijama session performed by a certified practitioner Undergo follow-up at 4 and 12 weeks for clinical, hormonal, and ultrasound assessments For all participants: Complete laboratory tests, ultrasound scans, and questionnaires on PCOS symptoms and quality of life Report any side effects during and after the study period
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 22 Aug 2025
- Start date
- 1 Jan 2026
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Princess Nourah Bint Abdulrahman University
- NCT number
- NCT07169292
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 1 Jan 2026 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of anabolic or androgenic drugs.
Other illness
- Diagnosis of diabetes mellitus.
- Known coagulation disorders.
- History of undergoing dry cupping, wet cupping, or acupuncture in the past 6 months.
- History of surgical removal of both ovaries or the uterus.
- Cushing's syndrome.
- Hypothalamic or pituitary disorders causing amenorrhea.
- Primary ovarian insufficiency.
Lab values
- Hyperprolactinemia with serum levels above 1000 mIU/L.
- Anemia with hemoglobin levels less than 10 g/dL.
Other
- Known diagnosis of uncontrolled thyroid dysfunction.
- Elevated FSH levels above 20 mIU/mL.
- Pregnant or lactating women.
- Other causes of hyperandrogenism, including:
- Late-onset non-classic 21-hydroxylase deficiency (excluded clinically; lab investigation if clinically indicated).
- Ovarian androgen-secreting tumors.
Who the study is looking for
- Female participants.
- Aged 20 to 40 years.
- Diagnosed with Polycystic Ovary Syndrome (PCOS) according to the Rotterdam criteria.
- Willing to participate in the study and provide informed consent.
- Not using any of the following in the last month: (Hormonal medications for menstruation, Herbal menstrual remedies or Metformin).
Age in the registry: 20 years to 40 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| King Abdullah bin Abdulaziz University Hospital Coordinator of this site? Confirm its status | Riyadh | Saudi Arabia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.