NCT07172165Enrolling by invitation
A Multicenter Study to Optimize Microembolic Signal Classification Based on Double--Blind Multiparametric Assessment by Human Experts Using an Universal Graphical Interface [MESOMEGA]
Source: ClinicalTrials.gov · Last updated 10 Dec 2025
Brief summary (registry, in English)
Microembolic signals (MES) is a powerful predictor of future embolic events. This study aims to develop and validate a accurate model of classification of MES obtained by transcranial Doppler. monitoring of However, MES detection is technically demanding and requires expert interpretation. By providing a reproducible framework for MES interpretation, this work aims to facilitate MES integration into future clinical trials and decision-making.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 850 (estimated)
- First submitted
- 27 Jun 2025
- Start date
- 15 May 2025
- Primary completion date
- 15 Dec 2025
- Lead sponsor
- Universidade do Porto
- Diseases
- Stroke
- NCT number
- NCT07172165
What you commit to
- Study type: Observational
- Planned participants: 850
- From 15 May 2025 to the primary completion date, 15 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of ultrasound contrast agent or agitated saline in the previous 24 hours
Other illness
- Obtained from patient during any cardiac surgery or endovascular procedure1
Other
- MES in gaseous form
- Obtained from patients with mechanical valve
- Obtained from patient with recent severe trauma
- Clips with multiples inseparable MES (e.g. curtain)
Who the study is looking for
- MES of presumed solid form or non-MES high intensity transient signals
- Obtained from on a human subject with age equal to or more than 18years old
- Obtained from proximal middle cerebral artery (M1 segment)
- Clip with 20 seconds duration with clearly event of interest marked using TCDPlayer
- With an overall background spectrum of reasonable quality to be analyzed
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Medicine University Porto Coordinator of this site? Confirm its status | Porto | Portugal | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.