NCT07172880Recruiting
Pregnancy 24/7 Offspring Study
Sedentary Behavior, Physical Activity, and 24-hour Behavior in Pregnancy and Offspring Health: the Pregnancy 24/7 Offspring Study
Source: ClinicalTrials.gov · Last updated 2 Nov 2026
Brief summary (registry, in English)
There is growing evidence that maternal health and behaviors in pregnancy, such as pre-pregnancy obesity, excessive gestational weight gain, poor diet, smoking, and adverse pregnancy outcomes, are linked to fetal programming for obesity and cardiovascular disease (CVD) risk in the offspring. Yet, there is a surprising lack of research on the role of prenatal sedentary behavior, physical activity, and sleep (conceptualized together as 24-hour behavior) on offspring obesity risk and CVD risk; this is an unfortunate research gap since there is strong physiological rationale that these behaviors in pregnancy could influence offspring health and are modifiable intervention targets in pregnancy. This multi-site observational cohort study will leverage state-of-the-art, 24-hour behavior assessment in each trimester of pregnancy, collected as part of the Pregnancy 24/7 cohort study and add additional assessments of offspring growth, adiposity, and CVD risk through 24 months to inform future primordial prevention interventions to decrease the risk of offspring obesity and CVD across the lifespan.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 800 (estimated)
- First submitted
- 8 Sept 2025
- Start date
- 1 Jul 2023
- Primary completion date
- 30 May 2027
- Lead sponsor
- Kara Whitaker
- Diseases
- Obesity
- NCT number
- NCT07172880
What you commit to
- Study type: Observational
- Planned participants: 800
- From 1 Jul 2023 to the primary completion date, 30 May 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Maternal Inclusion Criteria:
- Enrolled in Pregnancy 24/7 Study.
- Completed at least one 24-hr behavior assessment, with valid objective activity monitor data and questionnaires.
- Pregnancy resulted in singleton live birth.
- Offspring Exclusion Criteria:
- -Child diagnosed with congenital or chromosomal abnormalities that may affect growth or CVD risk.
Age in the registry: 0 years to 47 years · Sex: All · Accepts healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Iowa Coordinator of this site? Confirm its status | Iowa City | United States | Recruiting |
| West Virginia University Coordinator of this site? Confirm its status | Morgantown | United States | Recruiting |
| University of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Active, not recruiting |
Related publications
- Sedentary Behavior, Physical Activity, and Sleep During Pregnancy and Offspring Health: Protocol for the Pregnancy 24/7 Offspring Multi-Site Cohort Study.J Am Heart Assoc · 2026 · PMID 42857985
This page is information, not medical advice. Discuss any trial with your doctor.